Clare is Professor of Translational Cancer Genetics in the Division of Genetics and Epidemiology at the Institute of Cancer Research London and NHS honorary consultant.in clinical cancer genetics at The Royal Marsden NHS Foundation Trust, focusing on management of patients and families with genetic susceptibility to cancer. From 2014 to 2020, Clare worked at Genomics England as Clinical Lead for Cancer Genomics for the 100,000 Genomes Project.
Much of her research focuses on statistical, population and public-health-related analyses to better implement cancer susceptibility genetics for risk stratification, cancer early diagnosis and prevention. She has for the last 7 years had an honorary appointment at NHS Digital in the National Disease Registration Service (NDRS), leading on national amalgamation and analyses of variant data from all NHS diagnostic labs in England, supported by a multicentre CRUK-funded Catalyst Award: ‘CanGene-CanVar’. She also leads a number of NHS genomics transformation initiatives around simplifying pathways for BRCA-testing.
Clare studied undergraduate medicine at Cambridge, clinical medicine at Oxford, undertook a Masters in epidemiology and public health at the London School of Hygiene and Tropical Medicine and a PhD in statistical genetics at The Institute of Cancer Research.