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Pilot data from CCBRT Hospital, Dar es Salaam showed significantly lower levels of serum vitamin D in cases of TEON compared to healthy local controls; yet the healthy controls also had \u2018low\u2019 levels of serum vitamin D. The Tanzanian diet contains almost no vitamin D sources, hence vitamin D is a biomarker for sunlight exposure. But Tanzania lies just 6 degrees south of the equator, how can people have inadequate sunlight exposure? Evidence is mounting that urban, Sub-Saharan African populations are lacking in vitamin D and hence UV light exposure. UV light has effects independent of vitamin D and we plan to use our study to further investigate this.<\/p>\n
Thanks to the Fight for Sight\/RCOphth John Lee Primer Fellowship we are performing a pilot, case-control study in Dar es Salaam looking at a number of areas in relation to TEON:<\/p>\n
Our research involves looking at biomarkers of oxidative stress for the first time in TEON patients, as well as the first in-depth mitochondrial genetic analysis of these patients. With this unique approach to investigating TEON we hope to inform larger-scale studies and eventually produce an effective intervention for TEON patients.<\/p>\n
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Pilot data from CCBRT Hospital, Dar es Salaam showed significantly lower levels of serum vitamin D in cases of TEON compared to healthy local controls; yet the healthy controls also had \u2018low\u2019 levels of serum vitamin D. The Tanzanian diet contains almost no vitamin D sources, hence vitamin D is a biomarker for sunlight exposure. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-23","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/medicine.st-andrews.ac.uk\/teon\/wp-json\/wp\/v2\/pages\/23","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicine.st-andrews.ac.uk\/teon\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medicine.st-andrews.ac.uk\/teon\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medicine.st-andrews.ac.uk\/teon\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medicine.st-andrews.ac.uk\/teon\/wp-json\/wp\/v2\/comments?post=23"}],"version-history":[{"count":0,"href":"https:\/\/medicine.st-andrews.ac.uk\/teon\/wp-json\/wp\/v2\/pages\/23\/revisions"}],"wp:attachment":[{"href":"https:\/\/medicine.st-andrews.ac.uk\/teon\/wp-json\/wp\/v2\/media?parent=23"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}