{"id":453,"date":"2021-09-09T10:18:37","date_gmt":"2021-09-09T09:18:37","guid":{"rendered":"https:\/\/med.st-andrews.ac.uk\/research-groups\/?page_id=453"},"modified":"2021-09-09T10:18:37","modified_gmt":"2021-09-09T09:18:37","slug":"dominik-gurvic","status":"publish","type":"page","link":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/hammond\/people\/dominik-gurvic\/","title":{"rendered":"Dominik Gurvic"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Section – Hammond Menu” _builder_version=”4.9.10″ _module_preset=”default” background_color=”#0071b3″ min_height=”38px” max_height=”150px” custom_margin=”||-20px||false|false” custom_padding=”5px||0px||false|false” global_module=”180″ saved_tabs=”all” locked=”off”][et_pb_row _builder_version=”4.9.10″ _module_preset=”default” min_height=”81px”][et_pb_column type=”4_4″ _builder_version=”4.9.10″ _module_preset=”default”][et_pb_menu menu_id=”14″ active_link_color=”#ffffff” _builder_version=”4.9.10″ _module_preset=”default” menu_text_color=”#FFFFFF” menu_font_size=”18px” background_color=”#0071b3″ background_layout=”dark” custom_margin=”||||false|false”][\/et_pb_menu][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Section – Hammond Breadcrumbs” _builder_version=”4.9.4″ _module_preset=”default” locked=”off”][et_pb_row _builder_version=”4.9.4″ _module_preset=”default” custom_margin=”-50px|auto||auto|false|false” custom_padding=”10px||||false|false”][et_pb_column type=”4_4″ _builder_version=”4.9.4″ _module_preset=”default”][et_pb_text admin_label=”Research Breadcrumbs” _builder_version=”4.9.10″ _module_preset=”default” text_font_size=”16px” hover_enabled=”0″ content__hover_enabled=”off|desktop” sticky_enabled=”0″]Research Groups<\/a> > Hammond<\/a> > People<\/a> > Dominik Gurvic[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.9.10″ _module_preset=”default” custom_margin=”-110px||||false|false” border_color_all=”#d8d8d8″][et_pb_row column_structure=”1_3,2_3″ _builder_version=”4.9.10″ _module_preset=”default” collapsed=”off”][et_pb_column type=”1_3″ _builder_version=”4.9.10″ _module_preset=”default”][et_pb_image src=”https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-content\/uploads\/sites\/45\/2021\/09\/20210902-Dom.jpg” alt=”Dominik Gurvic” force_fullwidth=”on” _builder_version=”4.9.10″ _module_preset=”default” hover_enabled=”0″ title_text=”20210902-Dom” sticky_enabled=”0″][\/et_pb_image][et_pb_text admin_label=”Txt – Header” _builder_version=”4.9.10″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

Dominik Gurvic<\/b><\/h1>\n

[\/et_pb_text][et_pb_divider color=”#b7b7b7″ _builder_version=”4.9.10″ _module_preset=”default” custom_margin=”||-2px|||”][\/et_pb_divider][et_pb_text admin_label=”Email” _builder_version=”4.9.10″ _module_preset=”default” hover_enabled=”0″ content__hover_enabled=”on|hover” content__hover=”<\/p>\n

\n

Email
d.gurvic@dundee.ac.uk<\/b><\/span><\/a><\/p>\n<\/div>\n

” sticky_enabled=”0″]<\/p>\n

\n

Email
d.gurvic@dundee.ac.uk<\/b><\/u><\/span><\/a><\/p>\n<\/div>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”4.9.10″ _module_preset=”default”][et_pb_text admin_label=”Bio” _builder_version=”4.9.10″ _module_preset=”default” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n

Biography<\/strong><\/h1>\n

Dom is based in Computational Biology Division in School of Life Sciences in the University of Dundee in the lab of Prof. Ulrich Zachariae.<\/p>\n

His work is focused on antimicrobial resistance and development of antibiotics.<\/p>\n

He uses large datasets of compounds with associated antimicrobial activity to extract permeation patterns.\u00a0Which are then used to train machine learning algorithms,\u00a0to be able to predict similar permeation in other molecules.<\/p>\n

Chemoinformatic techniques such as matched pair analysis, molecular similarity calculations, physicochemical feature calculations\u00a0and in-house developed functional group analysis are used to detect structural determinants that lead to permeation.\u00a0Which will allow to predict possible new antimicrobial molecules more accurately and faster than conventional drug development.\u00a0 As well as allow to carry out alterations to existing drugs, in order to increase Gram-negative activity or avoid existing resistance pathways in pathogenic bacteria.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Research Groups > Hammond > People > Dominik GurvicDominik Gurvic Emaild.gurvic@dundee.ac.uk Biography Dom is based in Computational Biology Division in School of Life Sciences in the University of Dundee in the lab of Prof. Ulrich Zachariae. His work is focused on antimicrobial resistance and development of antibiotics. He uses large datasets of compounds with associated […]<\/p>\n","protected":false},"author":126,"featured_media":0,"parent":53,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-453","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-json\/wp\/v2\/pages\/453","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-json\/wp\/v2\/users\/126"}],"replies":[{"embeddable":true,"href":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-json\/wp\/v2\/comments?post=453"}],"version-history":[{"count":0,"href":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-json\/wp\/v2\/pages\/453\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-json\/wp\/v2\/pages\/53"}],"wp:attachment":[{"href":"https:\/\/medicine.st-andrews.ac.uk\/research-groups\/wp-json\/wp\/v2\/media?parent=453"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}