University of St Andrews

Cellular Medicine Research Division

CMED 5 Publications

Publications

50 (of 336 /dk/atira/pure/researchoutput/status/published available) for Cellular Medicine Division (source: University of St Andrews PURE)
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A signaling visualization toolkit to support rational design of combination therapies and biomarker discovery James L Brown, Mark Shovman, Paul Robertson, Andrei Boiko, Alexey Goltsov, Peter Mullen, David James Harrison
Oncotarget 2017 vol. 8 pp. 29657-29667
Influence of a high-fat diet on cardiac iNOS in female rats Aleksandra Jovanovic, Emina Sudar-Milovanovic, Milan Obradovic, Samantha J. Pitt, Alan J. Stewart, Sonja Zafirovic, Julijana Stanimirovic, Djordje Radak, Esma R. Isenovic
Current Vascular Pharmacology 2017 vol. 15 pp. 491-500
Polymorphisms in the F pocket of HLA-B27 subtypes strongly affect assembly, chaperone interactions and heavy-chain misfolding David B Guiliano, Helen North, Eleni Panayoitou, Elaine Catherine Campbell, Kirsty McHugh, Marine Silvestre, Paul Bowness, Simon John Powis, Antony N Antoniou
Arthritis & Rheumatology 2017 vol. 69 pp. 610-621
Genetics of human handedness and laterality Silvia Paracchini, Tom Scerri
2017 pp. 523-552
Lasing in live mitotic and non-phagocytic cells by efficient delivery of microresonators Marcel Schubert, Klara Volckaert, Andrew Morton, Gareth Brian Miles, Simon John Powis, Malte Christian Gather
Scientific Reports 2017 vol. 7
Evolutionary conservation and in vitro reconstitution of microsporidian iron-sulfur cluster biosynthesis Sven-A Freibert, Alina V. Goldberg, Christian Hacker, Sabine Molik, Paul Dean, Tom A. Williams, Sirintra Nakjang, Shaojun Long, Kacper Sendra, Eckhard Bill, Eva Heinz, Robert P. Hirt, T. Martin Embley, Roland Lill
Nature Communications 2017 vol. 8
Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002 Alexey Goltsov, Ghassan Tashkandi, Simon P Langdon, David James Harrison, James L Bown
European Journal of Pharmaceutical Sciences 2017 vol. 97 pp. 170-181
Skin colour changes during experimentally-induced sickness Julie Lasselin, Mats Lekander, Mats J Olsson, Simon John Powis, John Axelsson, David Ian Perrett
Brain, Behavior, and Immunity 2017 vol. 60
Biosynthesis of magnetic nanoparticles by human mesenchymal stem cells following transfection with the magnetotactic bacterial gene mms6 Alistair Elfick, Grigore Rischitor, Rabah Mouras, Asim Azfer, Lisa Lungaro, Marc Uhlarz, Thomas Herrmannsdörfer, Wesam Gamal, Pierre Bagnaninchi, Scott Semple, Donald M. Salter
Scientific Reports 2017 vol. 7
A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma Gabriela Gremel, Dijana Djureinovic, Marjut Niinivirta, Alexander Laird, Oscar Ljungqvist, Henrik Johannesson, Julia Bergman, Perk-Henrik Edqvist, Sanjay Navani, Naila Khan, Tushar Patil, Åsa Sivertsson, Mathias Uhlén, David James Harrison, Gustav J. Ullenhag, Grant D. Stewart, Fredrik Pontén
BMC Cancer 2017 vol. 17
Epigenetic sampling effects Christophe Van Neste, Alexander Laird, Fiach O'Mahony, Wim Van Criekinge, Dieter Deforce, Filip Van Nieuwerbugh, Thomas Powles, David James Harrison, Grant D. Stewart, Tim De Meyer
Cellular Oncology 2017 vol. 40 pp. 293-297
Multimodal discrimination of immune cells using a combination of Raman spectroscopy and digital holographic microscopy Mingzhou Chen, Simon John Powis, Kishan Dholakia
Scientific Reports 2017 vol. 7
17ß-Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats Sonja Zafirovic, Milan Obradovic, Emina Sudar-Milovanovic, Alexsandra Jovanovic, Julijana Stanimirovic, Alan J. Stewart, Samantha J. Pitt, Esma R. Isenovic
Molecular and Cellular Endocrinology 2017 vol. 446 pp. 12-20
Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells James Meehan, Carol Ward, Arran Turnbull, Jimi Bukowski-Wills, Andrew Finch, Edward J. Jarman, Chrysi Xintaropoulou, Carlos Martinez-Perez, Mark Gray, Matthew Pearson, Peter Mullen, Claudia T. Supuran, Fabrizio Carta, David James Harrison, Ian H. Kunkler, Simon Langdon
Oncotarget 2017 vol. 8 pp. 42857-42875
Quantifying Golgi structure using EM Anna M. Steyer, Terry M. Mayhew, Yannick Schwab,
Histochemistry and Cell Biology 2017 vol. 147 pp. 653-669
Enhanced imaging of lipid rich nanoparticles embedded in methylcellulose films for transmission electron microscopy using mixtures of heavy metals Jalal Asadi, Hussain Raja, Christian Hacker, Phedra Marius, Richard James Ward, Christos Pliotas, Jim Naismith,
Micron 2017 vol. 99 pp. 40-48
Long-term imaging of cellular forces with high precision by elastic resonator interference stress microscopy Nils Michael Kronenberg, Anja Steude, Johanna A Knipper, Jessica G Borger, Giuliano Scarcelli, Kristian Franze, Simon John Powis, Malte Christian Gather
Nature Cell Biology 2017 vol. 19 pp. 864-872
Overcoming intratumoural heterogeneity for reproducible molecular risk stratification Alexander L. R. Lubbock, Grant D. Stewart, Fiach C. O'Mahoney, Alexander Laird, Peter Mullen, Marie O'Donnell, Thomas Powles, David James Harrison, Ian M. Overton
BMC Medicine 2017 vol. 15
Changes in cardiac Na+/K+-ATPase expression and activity in female rats fed a high fat diet Aleksandra Jovanovic, Milan Obradovic, Emina Sudar-Milovanovic, Alan J. Stewart, Samantha J. Pitt, Dragan Alvantic, Ema Aleksic, Esma R. Isenovic
Molecular and Cellular Biochemistry 2017 vol. 436 pp. 49-58
The DCDC2 deletion is not a risk factor for dyslexia Thomas S. Scerri, Ellen Macpherson, Angela Martinelli, Wong Cheuk Wa, Anthony P. Monaco, John Stein, Mo Zheng, Connie Suk-Han Ho, Catherine McBride, Margaret Snowling, Charles Hulme, Marianna E. Hayiou-Thomas, Mary M.Y. Waye, Joel B. Talcott, Silvia Paracchini
Translational Psychiatry 2017 vol. 7
Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage Angela Karumbi, Connor McIntyre, Wojciech Bal, Miyuki Nishi, Hiroshi Takeshima, Alan J. Stewart, Samantha J. Pitt
Journal of Biological Chemistry 2017 vol. 292 pp. 13361-13373
Balance Right in Multiple Sclerosis (BRiMS): a guided self-management programme to reduce falls and improve quality of life, balance and mobility in people with secondary progressive multiple sclerosis H. Gunn, J. Andrade, L. Paul, L. Miller, S. Creanor, C. Green, J. Marsden, P. Ewings, M. Berrow, J Vickery, A. Barton, B. Marshall, John Peter Zajicek, J. A. Freeman
Pilot and Feasibility Studies 2017 vol. 4
New model for estimating glomerular filtration rate in patients with cancer Tobias Janowitz, Edward H. Williams, Andrea Marshall, Nicola Ainsworth, Peter B. Thomas, Stephen J. Sammut, Scott Shepherd, Jeff White, Patrick B. Mark, Andy Lynch, Duncan I. Jodrell, Simon Tavaré, Helena Earl
Journal of Clinical Oncology 2017 vol. 35 pp. 2798-2805
A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy Ayesha Noorani, Jan Bornschein, Andy Lynch, Maria Secrier, Achilleas Achilleos, Matthew Eldridge, Lawrence Bower, Jamie M.J. Weaver, Jason Crawte, Chin-Ann Ong, Nicholas Shannon, Shona MacRae, Nicola Grehan, Barbara Nutzinger, Maria O'Donovan, Richard Hardwick, Simon Tavaré, Rebecca C. Fitzgerald,
Genome Research 2017 vol. 27 pp. 902-912
DESNT Bogdan-Alexandru Luca, Daniel S. Brewer, Dylan R. Edwards, Sandra Edwards, Hayley C. Whitaker, Sue Merson, Nening Dennis, Rosalin A. Cooper, Steven Hazell, Anne Y. Warren, Rosalind Eeles, Andy Lynch, Helen Ross-Adams, Alastair D. Lamb, David E. Neal, Krishna Sethia, Robert D. Mills, Richard Y. Ball, Helen Curley, Jeremy Clark, Vincent Moulton, Colin S. Cooper
European Urology Focus 2018 vol. 4 pp. 842-850
The importance of DNA methylation in prostate cancer development Charles E. Massie, Ian G Mills, Andy Lynch
The Journal of Steroid Biochemistry and Molecular Biology 2017 vol. 166 pp. 1-15
Mining human prostate cancer datasets Mark J. Dunning, Sarah L. Vowler, Emilie Lalonde, Helen Ross-Adams, Paul Boutros, Ian G Mills, Andy Lynch, Alastair D. Lamb
EBioMedicine 2017 vol. 17 pp. 5-6
PLA2 and ENPP6 may act in concert to generate phosphocholine from the matrix vesicle membrane during skeletal mineralization Alan J. Stewart, Darren T K Leong, Colin Farquharson
FASEB Journal 2018 vol. 32 pp. 20-25
Genomic evolution of breast cancer metastasis and relapse Lucy R. Yates, Stian Knappskog, David Wedge, James H R Farmery, Santiago Gonzalez, Inigo Martincorena, Ludmil B. Alexandrov, Peter Van Loo, Hans Kristian Haugland, Peer Kaare Lilleng, Gunes Gundem, Moritz Gerstung, Elli Pappaemmanuil, Patrycja Gazinska, Shriram G Bhosle, David Jones, Keiran Raine, Laura Mudie, Calli Latimer, Elinor Sawyer, Christine Desmedt, Christos Sotiriou, Michael R. Stratton, Anieta M Sieuwerts, Andy Lynch, John W Martens, Andrea L. Richardson, Andrew Tutt, Per Eystein Lønning, Peter J. Campbell
Cancer Cell 2017 vol. 32 pp. 169-184
The major histocompatibility complex class I immunopeptidome of extracellular vesicles Silvia Anna Synowsky, Sally Lorna Shirran, Antony N. Antoniou, Catherine Helen Botting, Simon John Powis
Journal of Biological Chemistry 2017 vol. 292 pp. 17084-17092
The role of TET-mediated DNA hydroxymethylation in prostate cancer E Smeets, Andy Lynch, S Prekovic, T Van den Broeck, L Moris, C Helsen, S Joniau, F Claessens, C E Massie
Molecular and Cellular Endocrinology 2018 vol. 462 pp. 41-55
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer Mohammad Asim, Firas Tarish, Heather I. Zecchini, Kumar Sanjiv, Eleni Gelali, Charles E. Massie, Ajoeb Baridi, Anne Y. Warren, Wanfeng Zhao, Christoph Ogris, Leigh-Anne McDuffus, Patrice Mascalchi, Greg Shaw, Harveer Dev, Karan Wadhwa, Paul Wijnhoven, Josep V Forment, Scott R Lyons, Andy Lynch, Cormac O'Neill, Vincent R. Zecchini, Paul S. Rennie, Aria Baniahmad, Simon Tavaré, Ian G Mills, Yaron Galanty, Nicola Crosetto, Niklas Schultz, David Neal, Thomas Helleday
Nature Communications 2017 vol. 8
Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data Niedzica Camacho, Peter Van Loo, Sandra Edwards, Jonathan D Kay, Lucy Matthews, Kerstin Haase, Jeremy Clark, Nening Dennis, Sarah Thomas, Barbara Kremeyer, Jorge Zamora, Adam P. Butler, Gunes Gundem, Sue Merson, Hayley Luxton, Steve Hawkins, Mohammed Ghori, Luke Marsden, Adam Lambert, Katalin Karaszi, Gill Pelvender, Charlie E. Massie, Zsofia Kote-Jarai, Keiran Raine, David Jones, William J. Howat, Steven Hazell, Naomi Livni, Cyril Fisher, Christopher Ogden, Pardeep Kumar, Alan Thompson, David Nicol, Erik Mayer, Tim Dudderidge, Yongwei Yu, Hongwei Zhang, Nimish C. Shah, Vincent J. Gnanapragasam, The CRUK-ICGC Prostate Group, William Isaacs, Tapio Visakorpi, Freddie Hamdy, Dan Berney, Clare Verrill, Anne Y. Warren, David C. Wedge, Andy Lynch, Christopher S. Foster, Yong-Jie Lu, G. Steven Bova, Hayley C. Whitaker, Ultan McDermott, David E. Neal, Rosalind Eeles, Colin S. Cooper, Daniel S. Brewer
PLoS Genetics 2017 vol. 13
Multimode fibre based imaging for optically cleared samples Jonathan Nylk, Javier Ananda Tello, Kishan Dholakia
Biomedical Optics Express 2017 vol. 8 pp. 5179-5190
IDENTIFICATION OF GENETIC INTERACTIONS INVOLVED IN DYSLEXIA PATHOGENESIS Nazanin Karbalai, Darina Czamara, Kristina Moll, Franck Ramus, Rainer Malik, Thomas S Scerri, Johannes Schumacher, Andrew P. Morris, Thomas Bourgeron, Anthony P Monaco, Silvia Paracchini, Simon E Fisher, Markus Nothen, Gerd Schulte-Korne, Bertram Müller-Myhsok
European Neuropsychopharmacology 2017 vol. 27 pp. S183-S184
Integrative summary 3 Silvia Paracchini
2018 pp. 150-154
Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE Giulia Tamburrino, Salome Llabres, Owen Vickery, Samantha J. Pitt, Ulrich Zachariae
Scientific Reports 2017 vol. 7
Telomerecat James Farmery, Mike Smith, Andy Lynch
Scientific Reports 2018 vol. 8
Improving the quality of cognitive screening assessments C. G. . Newman, A. Bevins, John Peter Zajicek, J. Hodges, E. Vuillermoz, J. Dickenson, D. Kelly, S. Brown, R. Noad
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 2018 vol. 10 pp. 182-187
Light-sheet microscopy with attenuation-compensated propagation-invariant beams Jonathan Nylk, Miguel Preciado, Michael Mazilu, Zhengyi Yang, Frank J Gunn-Moore, Javier Ananda Tello, David Ellard Keith Ferrier, Kishan Dholakia
Science Advances 2018 vol. 4
Erythritol attenuates postprandial blood glucose by inhibiting α-glucosidase Huaixiu Wen, Bowen Tang, Alan J. Stewart, Yanduo Tao, Yun Shao, Yulei Cui, Huilan Yue, Jinjin Pei, Zenggen Liu, Lijuan Mei, Ruitao Yu, Lei Jiang
Journal of Agricultural and Food Chemistry 2018 vol. 66 pp. 1401-1407
The dyslexia susceptibility KIAA0319 gene shows a specific expression pattern during zebrafish development supporting a role beyond neuronal migration Monika Gostic, Angela Martinelli, Carl Tucker, Zhengyi Yang, Jade-Yi Ewart, Kishan Dholakia, Keith Thomas Sillar, Javier Ananda Tello, Silvia Paracchini
The Journal of Comparative Neurology 2019 vol. 527 pp. 2634-2643
Context based interpolation of coarse deep learning prediction maps for the segmentation of fine structures in immunofluorescence images Nicolas Brieu, David James Harrison, Peter David Caie, Guenter Schmidt
2018
Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degeneration Swati Arya, Eszter Emri, Silvia Anna Synowsky, Sally Lorna Shirran, Neda Barzegar-Befroei, Tunde Peto, Catherine Helen Botting, Imre Lengyel, Alan J. Stewart
Experimental Eye Research 2018 vol. 172 pp. 21-29
The neuronal migration hypothesis of dyslexia Luiz G. Guidi, Antonio Velayos-Baeza, Isabel Martinez-Garay, Anthony P. Monaca, Silvia Paracchini, Dorothy V.M. Bishop, Zoltán Molnár
European Journal of Neuroscience 2018 vol. 48 pp. 3212-3233
Glycosaminoglycan neutralization in coagulation control Amelie Isabelle Sylvie Sobczak, Samantha J. Pitt, Alan J. Stewart
Arteriosclerosis, Thrombosis, and Vascular Biology 2018 vol. 38 pp. 1258-1270
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets David C. Wedge, Gunes Gundem, Thomas Mitchell, Dan J. Woodstock, Inigo Martincorena, Mohammed Ghori, Jorge Zamora, Adam Butler, Hayley Whitaker, Zsofia Kote-Jarai, Lumil B. Alexandrov, Peter Van Loo, Charlie E. Massie, Stefan Dentro, Anne Y. Warren, Clare Verrill, Dan M. Berney, Nening Dennis, Sue Merson, Steve Hawkins, William Howat, Yong-Jie Lu, Adam Lambert, Jonathan Kay, Barbara Kremeyer, Katalin Karaszi, Niedzica Camacho, Hayley Luxton, Luke Marsden, Sandra Edwards, Lucy Matthews, Valeria Bo, Daniel Leongamornlert, Stuart McLaren, Anthony Ng, Yongwei Yu, Hongwei Zhang, Tokhir Dadaev, Sarah Thomas, Douglas F. Easton, Mahbubl Ahmed, Elizabeth Bancroft, Cyril Fisher, Naomi Livni, David Nicol, Simon Tavaré, Pelvender Gill, Christopher Greenman, Vincent Khoo, Nicholas Van As, Pardeep Kumar, Christopher Ogden, Declan Cahill, Alan Thompson, Erik Mayer, Edward Rowe, Tim Dudderidge, Vincent Gnanapragasam, Nimish C. Shah, Keiran Raine, David Jones, Andrew Menzies, Lucy Stebbings, Jon Teague, Steven Hazell, Cathy Corbishley, Johann de Bono, Gerhardt Attard, William Isaacs, Tapio Visakorpi, Michael Fraser, Paul C. Boutros, Robert G. Bristow, Paul Workman, Chris Sander, Freddie C. Hamdy, Andrew Futreal, Ultan McDermott, Bissan Al-Lazikani, Andy Lynch, G. Steven Bova, Christopher S. Foster, Daniel S. Brewer, David E. Neal, Colin S. Cooper, Rosalind A. Eeles
Nature Genetics 2018 vol. 50 pp. 682-692
Timing the landmark events in the evolution of clear cell renal cell cancer Thomas J. Mitchell, Samra Turajlic, Andrew Rowan, David Nicol, James H.R. Farmery, Tim O’Brien, Inigo Martincorena, Patrick Tarpey, Nicos Angelopoulos, Lucy R. Yates, Adam P. Butler, Keiran Raine, Grant D. Stewart, Ben Challacombe, Archana Fernando, Jose I. Lopez, Steve Hazell, Ashish Chandra, Simon Chowdhury, Sarah Rudman, Aspasia Soultati, Gordon Stamp, Nicos Fotiadis, Lisa Pickering, Lewis Au, Lavinia Spain, Joanna Lynch, Mark Stares, Jon Teague, Francesco Maura, David C. Wedge, Stuart Horswell, Tim Chambers, Kevin Litchfield, Hang Xu, Aengus Stewart, Reza Elaidi, Stéphane Oudard, Nicholas McGranahan, Istvan Csabai, Martin Gore, P. Andrew Futreal, James Larkin, Andy Lynch, Zoltan Szallasi, Charles Swanton, Peter J. Campbell
Cell 2018 vol. 173 pp. 611-623
Podocyte injury elicits loss and recovery of cellular forces Nils Michael Kronenberg, Mustafa Elshani, David James Harrison, Malte Christian Gather, Paul Andrew Reynolds
Science Advances 2018 vol. 4
Native electrospray mass spectrometry approaches to probe the interaction between zinc and an anti-angiogenic peptide from histidine-rich glycoprotein Esther M. Martin, Frances D. L. Kondrat, Alan J. Stewart, James H. Scrivens, Peter J. Sadler, Claudia A. Blindauer
Scientific Reports 2018 vol. 8

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