University of St Andrews


Multidisciplinary and collaborative approaches have been central to the continued success of medical research in St Andrews. Internationally recognised research programmes in various aspects of molecular medicine, psychology and community health sciences are currently being promoted and extended.

Strategically planned new staff appointments over the next decade, and our move to new purpose-built research facilities within the new Medical School building will provide the infrastructure and academic environment to ensure the sustained development and expansion of medical research in St Andrews in the future

Research themes


Latest Publications (50)

Humphris, GM 2015, ' Improving health professionals’ communication skills: a major global endeavour ' Patient Education and Counseling , vol 98, no. 1, pp. 1-2.
Sobota, A & Ozakinci, G 2014, ' Fertility and parenthood issues in young female cancer patients - a systematic review ' Journal of Cancer Survivorship , vol 8, no. 4, pp. 707-721.
Crombie, I, Falconer, D, Irvine, L, Williams, B, Ricketts, I , Humphris, GM , Norrie, J, Rice, P & Slane, P 2014, ' Behaviour change in 160 characters: a novel brief alcohol intervention for disadvantaged men ' Lancet , vol 384, pp. S26.
Tassie, E, Scotland, G, Brittenden, J, Cotton, SC, Elders, A, Campbell, MK, Campbell, B, Gough, M , Burr, JM , Ramsay, CR & CLASS Study Team 2014, ' Cost-effectiveness of ultrasound-guided foam sclerotherapy, endovenous laser ablation or surgery as treatment for primary varicose veins from the randomized CLASS trial ' British journal of surgery , vol 101, no. 12, pp. 1532-1540.
Zhou, Y & Humphris, GM 2014, ' Can reassurance hurt? ' Psychologist , vol 27, no. 11, pp. 842-845.
Zhou, Y , Black, R, Freeman, R, Herron, D , Humphris, GM , Menzies, R, Quinn, S, Scott, L & Waller, A 2014, ' Applying the Verona Coding Definitions of Emotional Sequences (VR-CoDES) in the dental context involving patients with complex communication needs: an exploratory study ' Patient Education and Counseling , vol 97, no. 2, pp. 180-187.
Hepburn, L, Prajsnar, TK, Klapholz, C, Moreno, P, Loynes, CA, Ogryzko, NV, Brown, K, Schiebler, M, Hegyi, K, Antrobus, R, Hammond, KL, Connolly, J, Ochoa, B, Bryant, C, Otto, M, Surewaard, B, Seneviratne, SL, Grogono, DM, Cachat, J, Ny, T, Kaser, A, Török, ME, Peacock, SJ , Holden, M , Blundell, T, Wang, L, Ligoxygakis, P, Minichiello, L, Woods, CG, Foster, SJ, Renshaw, SA & Floto, RA 2014, ' Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus ' Science , vol 346, no. 6209, pp. 641-6.
Gillespie, SH , Crook, AM, McHugh, TD, Mendel, CM, Meredith, SK, Murray, SR, Pappas, F, Phillips, PPJ & Nunn, AJ 2014, ' Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis ' New England Journal of Medicine , vol 371, no. 17, pp. 1577-1587.
Stewart, GD , Harrison, DJ , Swanton, C, Lewis, R, Bliss, J, Larkin, J & Nicol, DL 2014, ' Multidisciplinary urological engagement in translational renal cancer research ' Bju international , vol 114, no. 4, pp. 474-475.
Turkalp, Z, Karamchandani, J & Das, S 2014, ' IDH mutation in glioma: New insights and promises for the future ' JAMA Neurology , vol 71, no. 10, pp. 1319-1325.
Griffiths, G & Lucocq, JM 2014, ' Antibodies for immunolabeling by light and electron microscopy: not for the faint hearted ' Histochemistry and Cell Biology , vol 142, no. 4, pp. 347-360.
Morales, DR , Guthrie, B, Lipworth, BJ , Jackson, CM & Dreischulte, T 2014, ' Acute Topical beta-Blocker Exposure in Asthma: Meta-Analysis of Controlled Clinical Trials ' Pharmacoepidemiology and Drug Safety , vol 23, pp. 286-286.
Stones, W & Arulkumaran, S 2014, ' Health-care professionals in midwifery care ' Lancet , vol 384, no. 9949, pp. 1169-70.
Brittenden, J, Cotton, SC, Elders, A, Ramsay, CR, Norrie, J , Burr, J , Campbell, B, Bachoo, P, Chetter, I, Gough, M, Earnshaw, J, Lees, T, Scott, J, Baker, SA, Francis, J, Tassie, E, Scotland, G, Wileman, S & Campbell, MK 2014, ' A randomized trial comparing treatments for varicose veins ' New England Journal of Medicine , vol 371, no. 13, pp. 1218-1227.
O'Hare, BA-M 2014, ' Discordance between clinical and immunological ART eligibility criteria for children in Malawi ' BMC Research Notes .
Castillo, MM, Mowatt, G, Lois, N, Elders, A, Fraser, C, Amoaku, W , Burr, JM , Lotery, AJ, Ramsay, CR & Azuara-Blanco, A 2014, ' Optical coherence tomography for the diagnosis of neovascular age-related macular degeneration: a systematic review ' Eye (London, England) .
O'Hare, BA-M 2014, ' Health spending, illicit financial flows and tax incentives in Malawi ' Malawi medical journal .
Humphris, GM & Williams, B 2014, ' Is disgust the driver behind the selection of images for UK tobacco packets? ' Health Education Journal , vol 73, no. 5, pp. 522-529.
Laidlaw, AH , Hunter, J, Turvey, T, Stillman, M, Warren, R & Ozakinci, G 2014, ' The development and evaluation of a flexible training course: "Understanding and developing compassion" ' Journal of Evidence-Based Psychotherapies , vol 14, no. 2, pp. 149-157.
Cecil, JE , McHale, CT, Hart, J & Laidlaw, AH 2014, ' Behaviour and burnout in medical students ' Medical Education Online , vol 19, 25209.
Monsanto Pinheiro, M , Divis, PC, Siner, A, Zainudin, R, Wong, IT, Lu, CW, Singh-Khaira, SK, Millar, SB, Lynch, S, Willmann, M, Singh, B, Krishna, S & Cox Singh, J 2014, ' Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members ' PLoS Neglected Tropical Diseases , vol 8, no. 8, e3086.
Lawn, JE, Segre, J, Barker, P, Smith, J, De La Torre, I & Stones, W 2014, ' Antenatal corticosteroids to reduce preterm deaths in low-income settings ' The Lancet Global Health , vol 2, no. 8, pp. E446-E446.
Levin, KA 2014, ' Urban-rural differences in adolescent eating behaviour: a multilevel cross-sectional study of 15-year-olds in Scotland ' Public Heath Nutrition , vol 17, no. 8, pp. 1776-1785.
Wang, Z , Luo, H, Nick, M, Gueorguieva, M , Andre, P , Baker, RT , McLean, D, Brown, S & Cuschieri, A 2014, ' Electrical conductivity measurement in Thiel-embalmed tissue model: Relevance to radiofrequency ablation ' Electronics Letters , vol 50, no. 16, pp. 1125-1127.
Gialluisi, A, Newbury, DF, Wilcutt, EG, Olson, RK, DeFries, JC, Brandler, WM, Pennington, BF, Smith, SD, Scerri, TS, Simpson, NH, Luciano, M, Evans, DM, Bates, TC, Stein, JF, Talcott, JB, Monaco, AP , Paracchini, S , Francks, C, Fisher, SE & The SLI Consortium 2014, ' Genome-wide screening for DNA variants associated with reading and language traits ' GENES BRAIN AND BEHAVIOR .
Cavanagh, JP, Hjerde, E , Holden, MTG , Kahlke, T, Klingenberg, C, Flægstad, T, Parkhill, J, Bentley, SD & Sollid, JUE 2014, ' Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus haemolyticus in European hospitals ' Journal of Antimicrobial Chemotherapy .
Martin, J, Cooper, M, Hamshere, ML, Pocklington, A, Scherer, SW , Kent, L , Gill, M, Owen, MJ, Williams, N, O'Donovan, MC, Thapar, A & Holmans, P 2014, ' Biological Overlap of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder: Evidence From Copy Number Variants ' Journal of the American Academy of Child and Adolescent Psychiatry , vol 53, no. 7, pp. 761-770.
Bossé, JT, Li, Y, Angen, O, Weinert, LA, Chaudhuri, RR, Holden, MT, Williamson, SM, Maskell, DJ, Tucker, AW, Wren, BW, Rycroft, AN, Langford, PR, on behalf of the BRaDP1T consortium & Holden, M 2014, ' Multiplex PCR Assay for unequivocal differentiation of Actinobacillus pleuropneumoniae serovars 1 to 3, 5 to 8, 10, and 12 ' Journal of Clinical Microbiology , pp. 2380-2385.
Beaton, L, Freeman, R & Humphris, GM 2014, ' Why are people afraid of the dentist? Observations and explanations ' Medical Principles and Practice , vol 23, no. 4.
McClinton, S, Starr, K, Thomas, R, McLennan, G, McPherson, G, McDonald, A, Lam, T, N'Dow, J, Kilonzo, M, Pickard, R, Anson, K & Burr, J 2014, ' Use of drug therapy in the management of symptomatic ureteric stones in hospitalized adults (SUSPEND), a multicentre, placebo-controlled, randomized trial of a calcium-channel blocker (nifedipine) and an alpha-blocker (tamsulosin): study protocol for a randomized controlled trial ' Trials , vol 15, 238.
Koussounadis, A , Langdon, SP , Harrison, DJ & Smith, VA 2014, ' Chemotherapy-induced dynamic gene expression changes in vivo are prognostic in ovarian cancer ' British Journal of Cancer , vol 110, no. 12, pp. 2975-2984.
Goltsov, A, Deeni, Y, Khalil, HS, Soininen, T, Kyriakidis, S, Hu, H, Langdon, SP , Harrison, DJ & Bown, J 2014, ' Systems analysis of drug-induced receptor tyrosine kinase reprogramming following targeted mono- and combination anti-cancer therapy ' Cells , vol 3, no. 2, pp. 563-591.
Caie, PD, Turnbull, AK, Farrington, SM , Oniscu, A & Harrison, DJ 2014, ' Quantification of tumour budding, lymphatic vessel density and invasion through image analysis in colorectal cancer ' Journal of Translational Medicine , vol 12, no. 1, 156.
O'Hare, BA-M , Makuta, I, Chiwaula, L & Bar-Zeev, N 2014, ' Upstream barriers to child mortality reduction: the case of Sub Saharan Africa ' Archives of disease in childhood , vol 99, no. Suppl. 1, A123 .
Denniston, AK, Kyte, D, Calvert, M & Burr, JM 2014, ' An introduction to patient-reported outcome measures in ophthalmic research ' Eye (London, England) , vol 28, no. 6, pp. 637-45.
Quaglio, G , Ramsay, A , Harries, AD, Karapiperis, T, Putoto, G, Dye, C, Olesen, OF, Tomson, G & Zachariah, R 2014, ' Calling on Europe to support operational research in low-income and middle-income countries ' The Lancet Global Health , vol 2, no. 6, pp. e308-3310.
Cote, CL, Castonguay, M, Kalujnaia, MS , Cramb, G & Bernatchez, L 2014, ' In absence of local adaptation, plasticity and spatially varying selection rule: a view from genomic reaction norms in a panmictic species (Anguilla rostrata) ' BMC Genomics , vol 15, 403.
Pitt, SJ , Lam, AKM, Rietdorf, K, Galione, A & Sitsapesan, R 2014, ' Reconstituted human TPC1 is a proton-permeable ion channel and is activated by NAADP or Ca 2+ ' Science signaling , vol 7, no. 326, ra46.
Harrison, EM, Weinert, LA , Holden, MTG , Welch, JJ, Wilson, K, Morgan, FJE, Harris, SR, Loeffler, A, Boag, AK, Peacock, SJ, Paterson, GK, Waller, AS, Parkhill, J & Holmes, MA 2014, ' A shared population of epidemic methicillin-resistant Staphylococcus aureus 15 circulates in humans and companion animals ' Mbio , vol 5, no. 3, e00985-13 .
Ross, MT, Macrae, C, Scott, J, Renwick, L, Moffat, M, Needham, G, Scott, H, Shippey, B , Jackson, C , Edgar, S, Aitken, D, Evans, P & Irvine, S 2014, ' Core competencies in teaching and training for doctors in Scotland: a review of the literature and stakeholder survey ' Medical Teacher , vol 36, no. 6, pp. 527-538.
Uhlemann, A-C, Dordel, J, Knox, JR, Raven, KE, Parkhill, J , Holden, MTG , Peacock, SJ & Lowy, FD 2014, ' Molecular tracing of the emergence, diversification, and transmission of S. aureus sequence type 8 in a New York community ' Proceedings of the National Academy of Sciences of the United States of America , vol 111, no. 18, pp. 6738–6743.
Obradovic, M , Stewart, AJ , Pitt, SJ , Labudovic-Borovic, M, Sudar, E, Petrovic, V, Zafirovic, S, Maravic-Stojkovic, V, Vasic, V & Isenovic, ER 2014, ' In vivo effects of 17β-estradiol on cardiac Na + /K + -ATPase expression and activity in rat heart ' Molecular and Cellular Endocrinology , vol 388, no. 1-2, pp. 58-68.
Sabiiti, W , Robertson, E, Beale, MA, Johnston, SA, Brouwer, AE, Loyse, A, Jarvis, JN, Gilbert, AS, Fisher, MC, Harrison, TS, May, RC & Bicanic, T 2014, ' Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis ' The Journal of Clinical Investigation , vol 124, no. 5, pp. 2000-8.
Vettenburg, T , Dalgarno, HIC , Nylk, J, Coll-Lladó, C , Ferrier, DEK , Cizmar, T , Gunn-Moore, FJ & Dholakia, K 2014, ' Light-sheet microscopy using an Airy beam ' Nature Methods , vol 11, no. 5, pp. 541-544.
Cecil, JE 2014, ' Applying learning theory to improve liking and intake of vegetables in children ' Appetite , vol 76, no. 1 May 2014.
Neville, FG 2014, ' Examination into the effectiveness of transdermal alcohol monitoring upon violent offending ' Paper presented at New Directions in the Study of Alcohol Group, United Kingdom, 25/04/14 , .
Hart, AB, Gamazon, ER, Engelhardt, BE, Sklar, P, Kähler, AK, Hultman, CM, Sullivan, PF, Neale, BM, Faraone, SV, de Wit, H, Cox, NJ, Palmer, AA, Psychiatric Genomics Consortium: ADHD Subgroup & Kent, L 2014, ' Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder ' Proceedings of the National Academy of Sciences of the United States of America , vol 111, no. 16, pp. 5968-73.
Williams, DJ , Re, D & Ozakinci, G 2014, ' Television viewing habits of pre-clinical UK medical undergraduates: Further potential implications for bioethics ' American Journal of Bioethics: Empirical Bioethics , vol 5, no. 2, pp. 55-67.
Bucksch, J , Inchley, J , Hamrik, Z, Finne, E, Kolip, P & HBSC Study Group Germany 2014, ' Trends in television time, non-gaming PC use and moderate-to-vigorous physical activity among German adolescents 2002-2010 ' BMC Public Health , vol 14, no. 1, pp. 351.
Huang, R, Faratian, D, Sims, AH, Wilson, D, Thomas, JS , Harrison, DJ & Langdon, SP 2014, ' Increased STAT1 signaling in endocrine-resistant breast cancer ' PLoS One , vol 9, no. 4, e94226.