University of St Andrews


Multidisciplinary and collaborative approaches have been central to the continued success of medical research in St Andrews. Internationally recognised research programmes in various aspects of molecular medicine, psychology and community health sciences are currently being promoted and extended.

Strategically planned new staff appointments over the next decade, and our move to new purpose-built research facilities within the new Medical School building will provide the infrastructure and academic environment to ensure the sustained development and expansion of medical research in St Andrews in the future

Research themes


Latest Publications (50)

Obradovic, M , Stewart, AJ , Pitt, SJ , Labudovic-Borovic, M, Sudar, E, Petrovic, V, Zafirovic, S, Maravic-Stojkovic, V, Vasic, V & Isenovic, ER 2014, ' In vivo effects of 17β-estradiol on cardiac Na + /K + -ATPase expression and activity in rat heart ' Molecular and Cellular Endocrinology , vol 388, pp. 58-68.
Cecil, JE 2014, ' Applying learning theory to improve liking and intake of vegetables in children ' Appetite , vol 76, no. 1 May 2014.
Laabei, M, Recker, M, Rudkin, JK, Aldeljawi, M, Gulay, Z, Sloan, TJ, Williams, P, Endres, JL, Bayles, KW, Fey, PD, Yajjala, VK, Widhelm, T, Hawkins, E, Lewis, K, Parfett, S, Scowen, L, Peacock, SJ , Holden, M , Wilson, D, Read, TD, van den Elsen, J, Priest, NK, Feil, EJ, Hurst, LD, Josefsson, E & Massey, RC 2014, ' Predicting the virulence of MRSA from its genome sequence ' Genome Research .
Kassaar, O, McMahon, SA, Thompson, R , Botting, CH , Naismith, JH & Stewart, AJ 2014, ' Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: Implications for angiogenic regulation ' Blood , vol 123, pp. 1948-1955.
Sally Haw, Amanda Amos, Douglas Eadie, John Frank, Laura MacDonald, Anne Marie MacKintosh, Andy MacGregor, Jamie Pearce, Clare Sharp, Martin Stead, Catherine Tisch & van der Sluijs, W 2014, ' Determining the impact of smoking point of sale legislation among youth (Display) study: a protocol for an evaluation of public health policy ' BMC Public Health , vol 14, no. 251.
Esa, R, Leng Ong, A , Humphris, GM & Freeman, R 2014, ' The relationship of dental caries and dental fear in Malaysian adolescents: a latent variable approach ' BMC Oral Health , vol 14.
Popovics, P, Lu, J, Kamil, LN, Morgan, K, Millar, RP, Schmid, R, Blindauer, CA & Stewart, AJ 2014, ' A canonical EF-loop directs Ca 2+ -sensitivity in phospholipase C-η2 ' Journal of Cellular Biochemistry , vol 115, pp. 557–565.
Ba, X, Harrison, EM, Edwards, GF , Holden, MTG , Larsen, AR, Petersen, A, Skov, RL, Peacock, SJ, Parkhill, J, Paterson, GK & Holmes, MA 2014, ' Novel mutations in penicillin-binding protein genes in clinical Staphylococcus aureus isolates that are methicillin resistant on susceptibility testing, but lack the mec gene ' Journal of Antimicrobial Chemotherapy , vol 69, no. 3, pp. 594-7.
Nudel, R, Simpson, NH, Baird, G, O'Hare, A, Conti-Ramsden, G, Bolton, PF, Hennessy, ER, Ring, SM, Smith, GD, Francks, C , Paracchini, S , Monaco, AP, Fisher, SE, Newbury, DF & the SLI Consortium 2014, ' Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment ' GENES BRAIN AND BEHAVIOR .
Venturi, E, Galfré, E, O'Brien, F , Pitt, SJ , Bellamy, S, Sessions, RB & Sitsapesan, R 2014, ' FKBP12.6 Activates RyR1:Investigating the Amino Acid Residues Critical for Channel Modulation ' Biophysical Journal , vol 106, no. 4, pp. 824-33.
Ward, R , Pliotas, C , Branigan, E , Hacker, C , Rasmussen, A, Hagelueken, G, Booth, IR, Miller, S , Lucocq, J , Naismith, J & Schiemann, O 2014, ' Probing the structure of the mechanosensitive channel of small conductance in lipid bilayers with pulsed electron-electron double resonance ' Biophysical Journal , vol 106, no. 4, pp. 834-42.
Kappagantula, S , Andrews, MR , Cheah, M, Abad-Rodriguez, J, Dotti, CG & Fawcett, JW 2014, ' Neu3 Sialidase-Mediated Ganglioside Conversion Is Necessary for Axon Regeneration and Is Blocked in CNS Axons ' The Journal of Neuroscience , vol 34, no. 7, pp. 2477-2492.
van Hal, SJ, Steen, JA, Espedido, BA, Grimmond, SM, Cooper, MA , Holden, MTG , Bentley, SD, Gosbell, IB & Jensen, SO 2014, ' In vivo evolution of antimicrobial resistance in a series of Staphylococcus aureus patient isolates: the entire picture or a cautionary tale? ' Journal of Antimicrobial Chemotherapy , vol 69, no. 2, pp. 363-7.
Gordon, V , Williams, DJ & Donnelly, PD 2014, ' Relationship between ADHD symptoms and anti-social behaviour in a sample of older youths in adult Scottish prisons ' Personality and Individual Differences , vol 58, pp. 116-121.
Brandler, WM & Paracchini, S 2014, ' The genetic relationship between handedness and neurodevelopmental disorders ' Trends in Molecular Medicine , vol 20, no. 2, pp. 83-90.
Laidlaw, AH , Salisbury, H, Doherty, EM & Wiskin, C 2014, ' National survey of clinical communication assessment in medical education in the United Kingdom (UK) ' BMC Medical Education , vol 14, 10.
Paquete, L, Matias, P, Abbasi, M & Monsanto Pinheiro, M 2014, ' MOSAL: software tools for multiobjective sequence alignment ' Source Code for Biology and Medicine , vol 9, 2.
Ozgur Polat, P & Ozakinci, G 2014, ' Bilissel Duygu Duzenleme ve Kaygi Iliskisinde Araci Degisken Olarak Farkindalik Temelli Dusunme ' 18th National Psychology Congress, Bursa, Turkey, 9/04/14 - 12/04/14 , .
Dordel, J, Kim, C, Chung, M, Pardos de la Gándara, M , Holden, MTJ , Parkhill, J, de Lencastre, H, Bentley, SD & Tomasz, A 2014, ' Novel Determinants of Antibiotic Resistance: Identification of Mutated Loci in Highly Methicillin-Resistant Subpopulations of Methicillin-Resistant Staphylococcus aureus ' Mbio , vol 5, no. 2.
Newbury, DF, Monaco, AP & Paracchini, S 2014, ' Reading and language disorders: the importance of both quantity and quality ' Genes , vol 5, no. 2, pp. 285-309.
Vettenburg, T , Dalgarno, HIC , Nylk, J, Coll-Lladó, C , Ferrier, DEK , Cizmar, T , Gunn-Moore, FJ & Dholakia, K 2014, ' Light-sheet microscopy using an Airy beam ' Nature Methods .
Alves, JN, Muir, EM , Andrews, MR , Ward, A, Michelmore, N, Dasgupta, D, Verhaagen, J, Moloney, EB, Keynes, RJ, Fawcett, JW & Rogers, JH 2014, ' AAV vector-mediated secretion of chondroitinase provides a sensitive tracer for axonal arborisations ' Journal of Neuroscience Methods .
Muldoon, JC , Williams, JM & Lawrence, A 2014, ' ‘Mum cleaned it and I just played with it’: Children’s perceptions of their roles and responsibilities in the care of family pets ' Childhood .
Levin, KA , Dundas, R , Miller, MA & McCartney, G 2014, ' Socioeconomic and geographic inequalities in adolescent smoking: A multilevel cross-sectional study of 15 year olds in Scotland ' Social Science and Medicine .
Levin, KA & Currie, C 2014, ' Reliability and Validity of an Adapted Version of the Cantril Ladder for Use with Adolescent Samples ' Social Indicators Research .
Hanning, K , Steel, CM , Goudie, D, McLeish, L, Dunlop, J, Myring, J, Sullivan, F, Berg, J , Humphris, GM & Ozakinci, G 2014, ' Why do women not return family history forms when referred to breast cancer genetics services? A mixed-method study ' HEALTH EXPECTATIONS .
Levin, KA 2014, ' Urban–rural differences in adolescent eating behaviour: a multilevel cross-sectional study of 15-year-olds in Scotland ' Journal of Public Health Nutrition .
Whitehead, RD , Ozakinci, G & Perrett, DI 2014, ' A randomized controlled trial of an appearance-based dietary intervention ' Health Psychology , vol 33, no. 1, pp. 99-102.
Köser, CU, Fraser, LJ, Ioannou, A, Becq, J, Ellington, MJ , Holden, MTG , Reuter, S, Török, ME, Bentley, SD, Parkhill, J, Gormley, NA, Smith, GP & Peacock, SJ 2013, ' Rapid single-colony whole-genome sequencing of bacterial pathogens ' Journal of Antimicrobial Chemotherapy .
Roch, G , Tello, J & Sherwood, N 2013, ' At the transition from invertebrates to vertebrates a novel GnRH-like peptide emerges in amphioxus ' Molecular Biology and Evolution .
O'Hare, BA-M , Makuta, I, Bar-Zeev, N, Chiwaula, L & Cobham, A 2013, ' The effect of illicit financial flows on time to reach the fourth Millennium Development Goal in Sub-Saharan Africa: a quantitative analysis ' Journal of the Royal Society of Medicine , vol Early online.
Harrison, EM, Paterson, GK , Holden, MTG , Ba, X, Rolo, J, Morgan, FJE, Pichon, B, Kearns, A, Zadoks, RN, Peacock, SJ, Parkhill, J & Holmes, MA 2013, ' A novel hybrid SCCmec-mecC region in Staphylococcus sciuri ' Journal of Antimicrobial Chemotherapy .
Prior, M, Francis, JJ, Azuara-Blanco, A, Anand, N , Burr, JM & Glaucoma Screening Platform Study 2013, ' Why do people present late with advanced glaucoma? A qualitative interview study ' British Journal of Ophthalmology , vol 97, no. 12, pp. 1574-1578.
Bryant, JM, Harris, SR, Parkhill, J, Dawson, R, Diacon, A, van Helden, P, Pym, A, Ahmad Mahayiddin, A, Chuchottaworn, C, Sanne, IM, Louw, C, Boeree, MJ, Hoelscher, M, McHugh, TD, Bateson, ALC, Hunt, RD, Mwaigwisya, S, Wright, L , Gillespie, SH & Bentley, SD 2013, ' Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis : a retrospective observational study ' The Lancet Respiratory Medicine , vol 1, no. 10, pp. 786–792.
Coyle, CF , Humphris, GM & Freeman, R 2013, ' Dentists’ training and willingness to treat adolescents with learning disabilities: the mediating role of social and clinical factors ' Community Dental Health , pp. 263-268.
Caie, P, Schuur, K, Oniscu, A , Mullen, P , Reynolds, PA & Harrison, DJ 2013, ' Human tissue in systems medicine ' FEBS Journal , vol 280, no. 23, pp. 5949–5956.
Barnett, JP, Blindauer, CA, Kassaar, O , Khazaipoul, S , Martin, EM, Sadler, PJ & Stewart, AJ 2013, ' Allosteric modulation of zinc speciation by fatty acids ' Biochimica et Biophysica Acta - General Subjects , vol 1830, no. 12, pp. 5456-5464.
Peters Jr, T & Stewart, AJ 2013, ' Albumin research in the 21st century ' Biochimica et Biophysica Acta - General Subjects , vol 1830, no. 12, pp. 5351-5353.
Mellone, M, Kestoras, D , Andrews, MR , Dassie, E, Crowther, RA, Stokin, GB, Tinsley, J, Horne, G, Goedert, M, Tolkovsky, AM & Spillantini, MG 2013, ' Tau Pathology is Present In Vivo and Develops In Vitro in Sensory Neurons from Human P301S Tau Transgenic Mice: A System for Screening Drugs against Tauopathies ' The Journal of Neuroscience , vol 33, no. 46, pp. 18175-18189.
Molyneux, E & O'Hare, BA-M 2013, ' The value of including Global Health in the training of health professionals ' Archives of disease in childhood , vol 98, pp. 840-842.
Zhou, Y , Collinson, A , Laidlaw, AH & Humphris, GM 2013, ' How do medical students respond to emotional cues and concerns expressed by simulated patients during OSCE consultations? - A multilevel study ' PLoS One , vol 8, no. 10, e79166, pp. 1-9.
Simpson, NH, Addis, L, Brandler, WM, Slonims, V, Clark, A, Watson, J, Scerri, TS, Hennessy, ER, Bolton, PF, Conti-Ramsden, G, Fairfax, BP, Knight, JC, Stein, J, Talcott, JB, O'Hare, A, Baird, G , Paracchini, S , Fisher, SE, Newbury, DF & Consortium, S 2013, ' Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia ' Developmental Medicine and Child Neurology .
O'Carroll, V , Smith, J , Collinson, A , Jackson, CM & Ker, J 2013, ' Interprofessional Education for Students’ in Primary Care Placements: Widening Opportunities for Accessible Interprofessional Learning ' Medical Science Educator , vol 23, no. 3S, pp. 405-410.
Levin, KA 2013, ' Trends in Scottish adolescents' fruit and vegetable consumption and school effects ', pp. 4, International Fruit and Vegetable Alliance (IFAVA) Scientific Newsletter , 82.
Brandler, W, Morris, A, Evans, D, Scerri, T, Kemp, J, Timpson, N, St Pourcain, B, Davey Smith, G, Ring, S, Stein, J, Monaco, A, Talcott, J, Fisher, S, Webber, C & Paracchini, S 2013, ' Common Variants in Left/Right Asymmetry Genes and Pathways Are Associated with Relative Hand Skill ' PLoS Genetics , vol 9, no. 9, e10033751.
Becker, J, Czamara, D, Scerri, TS, Ramus, F, Csépe, V, Talcott, JB, Stein, J, Morris, A, Ludwig, KU, Hoffmann, P, Honbolygó, F, Tóth, D, Fauchereau, F, Bogliotti, C, Iannuzzi, S, Chaix, Y, Valdois, S, Billard, C, George, F, Soares-Boucaud, I, Gérard, C-L, van der Mark, S, Schulz, E, Vaessen, A, Maurer, U, Lohvansuu, K, Lyytinen, H, Zucchelli, M, Brandeis, D, Blomert, L, Leppänen, PH, Bruder, J, Monaco, AP, Müller-Myhsok, B, Kere, J, Landerl, K, Nöthen, MM, Schulte-Körne, G , Paracchini, S , Peyrard-Janvid, M & Schumacher, J 2013, ' Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort ' European Journal of Human Genetics .
Joseph, N , Tello, J , Bedecarrats, G & Millar, R 2013, ' Reproductive neuropeptides: Prevalence of GnRH and KNDy neural signalling components in a model avian, gallus gallus ' General and Comparative Endocrinology , vol 190, pp. 134-43.
Obradovic, M , Bjelogrlic, P , Rizzo, M, Katsiki, N, Haidara, M , Stewart, AJ , Jovanovic, A & Isenovic, ER 2013, ' Effects of obesity and estradiol on Na + /K + -ATPase and their relevance to cardiovascular disease. ' Journal of Endocrinology , vol 218, pp. R13-R23.
Lee, SH, Ripke, S, Neale, BM, Faraone, SV, Purcell, SM, Perlis, RH, Mowry, BJ, Thapar, A, Goddard, ME, Witte, JS, Absher, D, Agartz, I, Akil, H, Amin, F, Andreassen, OA, Anjorin, A, Anney, R, Anttila, V, Arking, DE, Asherson, P, Azevedo, MH, Backlund, L, Badner, JA, Bailey, AJ, Banaschewski, T, Barchas, JD, Barnes, MR, Barrett, TB, Bass, N, Battaglia, A, Bauer, M, Bayes, M, Bellivier, F, Bergen, SE, Berrettini, W, Betancur, C, Bettecken, T, Biederman, J, Binder, EB, Black, DW, Blackwood, DHR, Bloss, CS, Boehnke, M, Boomsma, DI, Breen, G, Breuer, R, Bruggeman, R, Cormican, P, Buccola, NG, Buitelaar, JK, Bunney, WE, Buxbaum, JD, Byerley, WF, Byrne, EM, Caesar, S, Cahn, W, Cantor, RM, Casas, M, Chakravarti, A, Chambert, K, Choudhury, K, Cichon, S, Cloninger, CR, Collier, DA, Cook, EH, Coon, H, Cormand, B, Corvin, A, Coryell, WH, Craig, DW, Craig, IW, Crosbie, J, Cuccaro, ML, Curtis, D, Czamara, D, Datta, S, Dawson, G, Day, R, De Geus, EJ, Degenhardt, F, Djurovic, S, Donohoe, GJ, Doyle, AE, Duan, J, Dudbridge, F, Duketis, E, Ebstein, RP, Edenberg, HJ, Elia, J, Ennis, S, Etain, B, Fanous, A, Farmer, AE, Ferrier, IN, Flickinger, M, Fombonne, E, Foroud, T, Frank, J, Franke, B, Fraser, C, Freedman, R, Freimer, NB, Freitag, CM, Friedl, M, Frisen, L, Gallagher, L, Gejman, PV, Georgieva, L, Gershon, ES, Geschwind, DH, Giegling, I, Gill, M, Gordon, SD, Gordon-Smith, K, Green, EK, Greenwood, TA, Grice, DE, Gross, M, Grozeva, D, Guan, W, Gurling, H, De Haan, L, Haines, JL, Hakonarson, H, Hallmayer, J, Hamilton, SP, Hamshere, ML, Hansen, TF, Hartmann, AM, Hautzinger, M, Heath, AC, Henders, AK, Herms, S, Hickie, IB, Hipolito, M, Hoefels, S, Holmans, PA, Holsboer, F, Hoogendijk, WJ, Hottenga, J-J, Hultman, CM, Hus, V, Ingason, A, Ising, M, Jamain, S, Jones, EG, Jones, I, Jones, L, Tzeng, J-Y, Kaehler, AK, Kahn, RS, Kandaswamy, R, Keller, MC, Kennedy, JL, Kenny, E , Kent, L , Kim, Y, Kirov, GK, Klauck, SM, Klei, L, Knowles, JA, Kohli, MA, Koller, DL, Konte, B, Korszun, A, Krabbendam, L, Krasucki, R, Kuntsi, J, Kwan, P, Landen, M, Langstrom, N, Lathrop, M, Lawrence, J, Lawson, WB, Leboyer, M, Ledbetter, DH, Lee, PH, Lencz, T, Lesch, K-P, Levinson, DF, Lewis, CM, Li, J, Lichtenstein, P, Lieberman, JA, Lin, D-Y, Linszen, DH, Liu, C, Lohoff, FW, Loo, SK, Lord, C, Lowe, JK, Lucae, S, MacIntyre, DJ, Madden, PAF, Maestrini, E, Magnusson, PKE, Mahon, PB, Maier, W, Malhotra, AK, Mane, SM, Martin, CL, Martin, NG, Mattheisen, M, Matthews, K, Mattingsdal, M, McCarroll, SA, McGhee, KA, McGough, JJ, McGrath, PJ, McGuffin, P, McInnis, MG, McIntosh, A, McKinney, R, McLean, AW, McMahon, FJ, McMahon, WM, McQuillin, A, Medeiros, H, Medland, SE, Meier, S, Melle, I, Meng, F, Meyer, J, Middeldorp, CM, Middleton, L, Milanova, V, Miranda, A, Monaco, AP, Montgomery, GW, Moran, JL, Moreno-De-Luca, D, Morken, G, Morris, DW, Morrow, EM, Moskvina, V, Muglia, P, Muehleisen, TW, Muir, WJ, Mueller-Myhsok, B, Murtha, M, Myers, RM, Myin-Germeys, I, Neale, MC, Nelson, SF, Nievergelt, CM, Nikolov, I, Nimgaonkar, V, Nolen, WA, Noethen, MM, Nurnberger, JI, Nwulia, EA, Nyholt, DR, O'Dushlaine, C, Oades, RD, Olincy, A, Oliveira, G, Olsen, L, Ophoff, RA, Osby, U, Owen, MJ, Palotie, A, Parr, JR, Paterson, AD, Pato, CN, Pato, MT, Penninx, BW, Pergadia, ML, Pericak-Vance, MA, Pickard, BS, Pimm, J, Piven, J, Posthuma, D, Potash, JB, Poustka, F, Propping, P, Puri, V, Quested, DJ, Quinn, EM, Antoni Ramos-Quiroga, J, Rasmussen, HB, Raychaudhuri, S, Rehnstroem, K, Reif, A, Ribases, M, Rice, JP, Rietschel, M, Roeder, K, Roeyers, H, Rossin, L, Rothenberger, A, Rouleau, G, Ruderfer, D, Rujescu, D, Sanders, AR, Sanders, SJ, Santangelo, SL, Sergeant, JA, Schachar, R, Schalling, M, Schatzberg, AF, Scheftner, WA, Schellenberg, GD, Scherer, SW, Schork, NJ, Schulze, TG, Schumacher, J, Schwarz, M, Scolnick, E, Scott, LJ, Shi, J, Shilling, PD, Shyn, SI, Silverman, JM, Slager, SL, Smalley, SL, Smit, JH, Smith, EN, Sonuga-Barke, EJS, St Clair, D, State, M, Steffens, M, Steinhausen, H-C, Strauss, JS, Strohmaier, J, Stroup, TS, Sutcliffe, JS, Szatmari, P, Szelinger, S, Thirumalai, S, Thompson, RC, Todorov, AA, Tozzi, F, Treutlein, J, Uhr, M, van den Oord, EJCG, Van Grootheest, G, Van Os, J, Vicente, AM, Vieland, VJ, Vincent, JB, Visscher, PM, Walsh, CA, Wassink, TH, Watson, SJ, Weissman, MM, Werge, T, Wienker, TF, Wijsman, EM, Willemsen, G, Williams, N, Willsey, AJ, Witt, SH, Xu, W, Young, AH, Yu, TW, Zammit, S, Zandi, PP, Zhang, P, Zitman, FG, Zoellner, S, Devlin, B, Kelsoe, JR, Sklar, P, Daly, MJ, O'Donovan, MC, Craddock, N, Sullivan, PF, Smoller, JW, Kendler, KS, Wray, NR, Cross-Disorder Grp Psychiat Genomi & Int Inflammatory Bowel Dis Genetic 2013, ' Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs ' Nature Genetics , vol 45, no. 9, pp. 984-+.
Crombie, I, Falconer, D, Irvine, L, Williams, B, Ricketts, I , Humphris, GM , Norrie, J, Rice, P & Slane, P 2013, ' Reducing alcohol-related harm in disadvantaged men: development and feasibility assessment of a brief intervention delivered by mobile telephone ' Public Health Research , vol 1, no. 3.