Dr Wilber Sabiiti

Dr Wilber Sabiiti
Research fellow

My story and interest in Infectious disease research begins with Makerere University, Uganda where I graduated as a Biochemistry major and immediately joined Dr. Lali Ferdinand’s laboratory to investigate the pathogenesis of Buruli ulcer disease. This work opened my eyes to a new horizon of host – pathogen interaction and its importance in the disease process. To have a better understanding of this phenomenon I joined the Free University of Brussels, Belgium for Master of Science in Molecular biology with a focus on mechanisms of disease in humans.

Shortly after my graduation I joined the University of Antwerp’s Medical microbiology laboratory to evaluate commercially available molecular diagnostics for accurate detection of Methicillin resistant Staphlococcus aureus (MRSA) and Vancomycin resistant enterococci (VRE) for which the most accurate diagnostic was recommended for use in the Europe-wide clinical trials on combating antimicrobial resistance within communities and Hospitals.

Building on this great experience I joined Prof. Robin C. May laboratory at University of Birmingham UK for doctoral research on mechanisms of brain infection in Cryptococcosis, the knowledge and experience that has formed the basis of my recent work at St. Georges University of London, investigating pathogenicity markers of poor clinical outcome in HIV-associated Cryptococcal meningitis.

I am now excited to join Prof. Stephen Gillespie’s team in the fight against Tuberculosis (TB) and about working with Laboratory technologists, Scientists and Clinicians to improve TB diagnosis and treatment outcome in resource poor settings.

data source: symbiosis

Research Overview from research@st-andrews

Recent publications listed in research@st-andrews
Sabiiti, W, Mtafya, B, Kuchaka, D, Azam, K, Viegas, S, Mdolo, A, Farmer, E, Khonga, M, Evangelopoulos, D, Honeyborne, I, Rachow, A, Heinrich, N, Ntinginya, NE, Bhatt, N, Davies, GR, Jani, IV, McHugh, TD, Kibiki, G, Hoelscher, M, Gillespie, SH & on behalf of the PANBIOME (Pan-African Biomarker Expansion Programme) consortium 2016, 'Optimising molecular diagnostic capacity for effective control of tuberculosis in high-burden settings' International Journal of Tuberculosis and Lung Disease, vol 20, no. 8, pp. 1004-1009. DOI: 10.5588/ijtld.15.0951
Beale, MA, Sabiiti, W, Robertson, EJ, Fuentes-Cabrejo, KM, O'Hanlon, SJ, Jarvis, JN, Loyse, A, Meintjes, G, Harrison, TS, May, RC, Fisher, MC & Bicanic, T 2015, 'Genotypic diversity is associated with clinical outcome and phenotype in cryptococcal meningitis across Southern Africa' PLoS Neglected Tropical Diseases, vol 9, no. 6, e0003847. DOI: 10.1371/journal.pntd.0003847
Sabiiti, W, Robertson, E, Beale, MA, Johnston, SA, Brouwer, AE, Loyse, A, Jarvis, JN, Gilbert, AS, Fisher, MC, Harrison, TS, May, RC & Bicanic, T 2014, 'Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis' The Journal of Clinical Investigation, vol 124, no. 5, pp. 2000-8. DOI: 10.1172/JCI72950
Malhotra-Kumar, S, Abrahantes, JC, Sabiiti, W, Lammens, C, Vercauteren, G, Ieven, M, Molenberghs, G, Aerts, M, Goossens, H & MOSAR WP2 Study Team 2010, 'Evaluation of chromogenic media for detection of methicillin-resistant Staphylococcus aureus' Journal of Clinical Microbiology, vol 48, no. 4, pp. 1040-6. DOI: 10.1128/JCM.01745-09