Dr Ruth Bowness

Dr Ruth Bowness
MRC Research Fellow



I graduated with a BSc in Mathematics from the University of St Andrews in 2005, and after Masters courses in Mathematics and Numerical Computing from the University of Cambridge and the University of Manchester, I returned to St Andrews to complete a PhD in Applied Maths. During my PhD I worked in the Solar group, my project involved numerically solving the Magnetohydrodynamic (MHD) equations in order to model solar phenomena.

I joined the Infection Group within the St Andrews Medical School in September 2012 to work on the PreDiCT-TB work programme, where I have been developing an appropriate mathematical framework within which data generated from experiments and tuberculosis clinical trials can be integrated. In this way we attempt to form template models that could help to form TB treatment plans and aid future drug development. Also working with the Mathematical Biology group in the School of Mathematics, my research involves using partial and ordinary differential equations, and individual-based models to describe infectious disease spread within the body and to simulate antibiotic treatment strategies. My current multidisciplinary project focuses on developing a spatial model to describe tuberculosis disease progression and treatment in the lungs. Ultimately the model will be capable of simulating new therapeutic approaches for multi-drug resistant tuberculosis.

data source: symbiosis

Research Overview from research@st-andrews

I am an MRC research fellow based in the School of Medicine at the University of St Andrews. My research interests lie in developing in host mathematical models for infectious diseases. Also working with the Mathematical Biology group in the School of Mathematics, my research involves using partial and ordinary differential equations, and individual-based models to describe infectious disease spread within the body and to simulate antibiotic treatment strategies. My current multidisciplinary project focuses on developing a spatial model to describe tuberculosis disease progression and treatment in the lungs. Ultimately the model will be capable of simulating new therapeutic approaches for multi-drug resistant tuberculosis.

 


Recent publications listed in research@st-andrews
7  (of 7 published available) for rec9. (source: University of St Andrews PURE)
Please click title of any item for full details

A spatially heterogeneous network-based metapopulation software model applied to the simulation of a pulmonary tuberculosis infection Ruth Bowness, Simon Andrew Dobson, Stephen Henry Gillespie
Applied Network Science 2018 vol.3 
Modelling the effects of bacterial cell state and spatial location on tuberculosis treatment Ruth Bowness, Mark Andrew Joseph Chaplain, Gibin G. Powathil, Stephen Henry Gillespie
Journal of Theoretical Biology 2018 vol.446 pp.87-100
Project Sanitarium Iain Donald, Karen Meyer, John Brengman, Stephen Henry Gillespie, Ruth Bowness
Journal of Computing in Higher Education 2017 vol.29 pp.599-617
Systems medicine and infection Ruth Bowness
 2016 pp.107-118
Project Sanitarium Iain Donald, Karen Meyer, Stephen Henry Gillespie, Ruth Bowness, John Brengman
 2015 
The relationship between Mycobacterium tuberculosis MGIT time to positivity and cfu in sputum samples demonstrates changing bacterial phenotypes potentially reflecting the impact of chemotherapy on critical sub-populations Ruth Bowness, Martin J Boeree, Rob Aarnoutse, Rodney Dawson, Andreas Diacon, Chacha Mangu, Norbert Heinrich, Nyanda E Ntinginya, Anke Kohlenberg, Bariki Mtafya, Patrick P J Phillips, Andrea Rachow, Georgette Plemper van Balen, Stephen Henry Gillespie
Journal of Antimicrobial Chemotherapy 2015 vol.70 pp.448-455
Coronal heating and nanoflares Ruth Bowness, Alan William Hood, Clare Elizabeth Parnell
Astronomy & Astrophysics 2013 vol.560