Mr Peter Mullen

Mr Peter Mullen
Research Fellow

data source: symbiosis

Research Overview from research@st-andrews

Recent publications listed in research@st-andrews
Meehan, J, Ward, C, Turnbull, A, Bukowski-Wills, J, Finch, A, Jarman, EJ, Xintaropoulou, C, Martinez-Perez, C, Gray, M, Pearson, M, Mullen, P, Supuran, CT, Carta, F, Harrison, DJ, Kunkler, IH & Langdon, S 2017, 'Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells' Oncotarget, vol. 8, no. 26, pp. 42857-42875. DOI: 10.18632/oncotarget.17143
Wilkie, RP, Neal, A, Johnston, CA, Voûte, N, Lancefield, CS, Stell, M, Medda, F, Makiyi, EF, Turner, E, Ojo, OS, Slawin, AMZ, Lebl, T, Mullen, P, Harrison, DJ, Ireland, CM & Westwood, NJ 2016, 'Total synthesis of dehaloperophoramidine using a highly diastereoselective Hosomi-Sakurai reaction' Chemical Communications, vol. 52, no. 71, pp. 10747-10750. DOI: 10.1039/c6cc05747k
Martínez-Pérez, C, Ward, C, Turnbull, AK, Mullen, P, Cook, G, Meehan, J, Jarman, EJ, Thomson, PIT, Campbell, CJ, McPhail, D, Harrison, DJ & Langdon, SP 2016, 'Antitumour activity of the novel flavonoid oncamex in preclinical breast cancer models' British Journal of Cancer, vol. 114, no. 8, pp. 905-916. DOI: 10.1038/bjc.2016.6
Stewart, GD, O'Mahony, F, Laird, A, Eory, L, Lubbock, A, Mackay, A, Nanda, J, O'Donnell, M, Mullen, P, McNeill, A, Riddick, A, Berney, D, Bex, A, Aitchison, M, Overton, IM, Harrison, DJ & Powles, T 2015, 'Sunitinib treatment exacerbates intratumoral heterogeneity in metastatic renal cancer' Clinical Cancer Research, vol. In press. DOI: 10.1158/1078-0432.CCR-15-0207
Ward, C, Meehan, J, Mullen, P, Supuran, C, Dixon, JM, Thomas, JS, Winum, J-Y, Lambin, P, Dubois, L, Pavathaneni, N-K, Jarman, EJ, Renshaw, L, Um, IH, Kay, C, Harrison, DJ, Kunkler, IH & Langdon, SP 2015, 'Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models' Oncotarget, vol. 6, no. 28, pp. 24865-24870.
Stewart, GD, O'Mahony, FC, Laird, A, Rashid, S, Martin, SA, Eory, L, Lubbock, ALR, Nanda, J, O'Donnell, M, Mackay, A, Mullen, P, McNeill, SA, Riddick, ACP, Aitchison, M, Berney, D, Bex, A, Overton, IM, Harrison, DJ & Powles, T 2014, 'Carbonic anhydrase 9 expression increases with vascular endothelial growth factor-targeted therapy and is predictive of outcome in metastatic clear cell renal cancer' European Urology, vol. 66, no. 5, pp. 956-963. DOI: 10.1016/j.eururo.2014.04.007
Stewart, G, Laird, A, O'Mahony, F, Eory, L, Lubbock, A, Nanda, J, O'Donnell, M, Mackay, A, Mullen, P, McNeill, A, Riddick, A, Aitchison, M, Berney, D, Bex, A, Overton, I, Harrison, DJ & Powles, T 2014, 'The effect of sunitinib on biomarkers and tumor heterogeneity in metastatic clear cell renal cancer.' Journal of Clinical Oncology, vol. 32, no. 4.
Caie, PD, Schuur, K, Oniscu, A, Mullen, P, Reynolds, PA & Harrison, DJ 2013, 'Human tissue in systems medicine' FEBS Journal, vol. 280, no. 23, pp. 5949–5956. DOI: 10.1111/febs.12550
Ward, C, Langdon, SP, Mullen, P, Harris, AL, Harrison, DJ, Supuran, CT & Kunkler, I 2013, 'New strategies for targeting the hypoxic tumour microenvironment in breast cancer' Cancer Treatment Reviews, vol. 39, no. 2, pp. 171-179. DOI: 10.1016/j.ctrv.2012.08.004
O'Mahony, FC, Nanda, J, Laird, A, Mullen, P, Caldwell, H, Overton, IM, Eory, L, O'Donnell, M, Faratian, D, Powles, T, Harrison, DJ & Stewart, GD 2013, 'The use of reverse phase protein arrays (RPPA) to explore protein expression variation within individual renal cell cancers' Journal of Visualized Experiments, no. 71. DOI: 10.3791/50221
Welman, A, Sproul, D, Mullen, P, Muir, M, Kinnaird, AR, Harrison, DJ, Faratian, D, Brunton, VG & Frame, MC 2012, 'Diversity of matriptase expression level and function in breast cancer' PLoS One, vol. 7, no. 4, e34182. DOI: 10.1371/journal.pone.0034182
Faratian, D, Zweemer, AJM, Nagumo, Y, Sims, AH, Muir, M, Dodds, M, Mullen, P, Um, I, Kay, C, Hasmann, M, Harrison, DJ & Langdon, SP 2011, 'Trastuzumab and Pertuzumab produce changes in morphology and estrogen receptor signaling in ovarian cancer xenografts revealing new treatment strategies' Clinical Cancer Research, vol. 17, no. 13, pp. 4451-4461. DOI: 10.1158/1078-0432.CCR-10-2461
Hochgraefe, F, Zhang, L, O'Toole, SA, Browne, BC, Pinese, M, Cubas, AP, Lehrbach, GM, Croucher, DR, Rickwood, D, Boulghourjian, A, Shearer, R, Nair, R, Swarbrick, A, Faratian, D, Mullen, P, Harrison, DJ, Biankin, AV, Sutherland, RL, Raftery, MJ & Daly, RJ 2010, 'Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells' Cancer Research, vol. 70, no. 22, pp. 9391-9401. DOI: 10.1158/0008-5472.CAN-10-0911