Prof Lindsey Kent
Professor of Molecular Psychiatry



I graduated in Medicine from Aberdeen University in 1989. After basic General Medicine and Psychiatry training, I obtained my PhD from the University of Birmingham in 1998. In 1999 I commenced a Wellcome Trust Fellowship in Psychiatric Genetics and subsequently moved to the University of Cambridge in 2003 as a University Lecturer. I was appointed as a Reader at the University of St Andrews in 2007 and promoted to Professor in 2009. I provide some clinical input into the General Adult Psychiatry service in Fife.

I am Deputy Head of the Medical School (Internal Affairs), the School Director of Admissions, and current Chair of the Scottish Medical Schools Admissions Group.

My research programme investigates the biological underpinnings of psychiatric disorders.

data source: symbiosis

Research Overview from research@st-andrews

I graduated in Medicine from Aberdeen University in 1989. After basic General Medicine and Psychiatry training, I obtained my PhD from the University of Birmingham in 1998. In 1999 I commenced a Wellcome Trust Fellowship in Psychiatric Genetics and subsequently moved to the University of Cambridge in 2003 as a University Lecturer. I was appointed as a Reader at the University of St Andrews in 2007 and promoted to Professor in 2009. I provide some clinical input into the General Adult Psychiatry service in Fife.

I am Deputy Head of the Medical School (Internal Affairs), the School Director of Admissions, and current Chair of the Scottish Medical Schools Admissions Group.

My research programme investigates the biological underpinnings of psychiatric disorders.


Recent publications listed in research@st-andrews
25 (of 84 published available) for lsk8 (source: University of St Andrews PURE)
Please click title of any item for full details

A case-control genome-wide association study of ADHD discovers a novel association with the tenascin R (TNR) gene Ziarih Hawi, Hannah Yates, Ari Pinar, Beth Johnson, Janette Tong, Kealan Pugsley, Callum Dark, Mark Pauper, Marieke Klein, Helen S Heussler, Alasdair Vance, Harriet Hiscock, Alex Fornito, Jeggan Tiego, Amy Finlay, Barbara Franke, Michael Gill, Lindsey Kent, Mark A. Bellgrove
Translational Psychiatry 2018 vol.8 
GLRB allelic variation associated with agoraphobic cognitions, increased startle response and fear network activation Jürgen Deckert, Heike Weber, Carmen Villmann, Tina B. Lonsdorf, Jan Richter, Marta Andreatta, Alejandro Arias-Vasquez, Leif Hommers, Lindsey Kent, Christoph Schartner, Sven Cichon, Christian Wolf, Natascha Schaefer, Cora R. von Collenberg, Britta Wachter, Robert Blum, Dirk Schümann, Robert Scharfenort, Johannes Schumacher, Andreas J. Forstner, Christian Baumann, Miriam A. Schiele, Swantje Notzon, Peter Zwanzger, Joost G.E. Janzing, Tessel Galesloot, Lambertus A. Kiemeney, Agnes Gajewska, Evelyn Glotzbach-Schoon, Andreas Mühlberger, Georg Alpers, Thomas Fydrich, Lydia Fehm, Alexander L. Gerlach, Tilo Kircher, Thomas Lang, Andreas Ströhle, Volker Arolt, Hans-Ulrich Wittchen, Raffael Kalisch, Christian Büchel, Alfons Hamm, Markus M. Nöthen, Marcel Romanos, Katharina Domschke, Pauli Pauli, Andreas Reif
Molecular Psychiatry 2017 pp.1431-1439
Rare DNA variants in the brain derived neurotrophic factor gene increase risk for attention deficit hyperactivity disorder Ziarih Hawi, Tarrant D R Cummins, Janette Tong, Mauricio Arcos-Burgos, Qiongyi Zhao, Natasha Matthews, Daniel P Newman, Beth Johnson, Alasdair Vance, Helen S Heussler, Florence Levy, Simon Easteal, Naomi Wray, Elaine Kenny, Derek Morris, Lindsey Kent, Michael Gill, Mark Bellgrove
Molecular Psychiatry 2017 vol.Advance online pp.580-584
Pathway analysis in attention deficit hyperactivity disorder Michael A Mooney, Shannon K McWeeney, Stephen V Faraone, Anke Hinney, Johannes Hebebrand, Joel T Nigg, beth wilmot, Lindsey Kent
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics  2016 vol.171 pp.815-826
Psychiatric gene discoveries shape evidence on ADHD's biology A Thapar, J Martin, E Mick, A Arias Vásquez, K Langley, S W Scherer, R Schachar, J Crosbie, N Williams, B Franke, J Elia, J Glessner, H Hakonarson, M J Owen, S V Faraone, M C O'Donovan, P Holmans, Lindsey Kent
Molecular Psychiatry 2016 vol.21 pp.1202-1207
Allelic variation in CRHR1 predisposes to panic disorder Heike Weber, Jan Richter, Benjamin Straube, Ulrike Lueken, Katharina Domschke, Christoph Schartner, Benedikt Klauke, Christian Baumann, Christiane Pané-Farré, Christian P. Jacob, Claus-Jürgen Scholz, Peter Zwanger, Thomas Lang, Lydia Fehm, Andreas Jansen, Carsten Konrad, Thomas Fydrich, Andre Wittman, Bettina Pfleiderer, Andreas Ströhle, Alexander L. Gerlach, Georg W. Alpers, Volker Arolt, Paul Pauli, Hans-Ulrich Wittchen, Lindsey Kent, Alfons Hamm, Tilo Kircher, Jürgen Deckert, Andreas Reif
Molecular Psychiatry 2015 
Converging evidence does not support GIT1 as an ADHD risk gene M. Klein, M. van der Voet, B. Harich, K.J.E. van Hulzen, A.M.H. Onnink, M. Hoogman, T. Guadalupe, M. Zwiers, J.M. Groothuismink, A. Verberkt, B. Nijhof, A. Castells-Nobau, S.V. Faraone, J.K. Buitelaar, A. Schenck, A. Arias-Vasquez, B. Franke, R.J.L. Anney, A.A. Vasquez, P. Asherson, T. Banaschewski, M. Bayés, J. Biederman, J.K. Buitelaar, M. Casas, A. Charach, B. Cormand, J. Crosbie, M.J. Daly, Alysa E. Doyle, R.P. Ebstein, J. Elia, S.V. Faraone, B. Franke, C. Freitag, M. Gill, H. Hakonarson, J. Hebebrand, A. Hinney, P. Holmans, Lindsey Kent, J. Kuntsi, N. Lambregts-Rommelse, K. Langley, K.-P. Lesch, S.K. Loo, J.J. McGough, S.E. Medland, J. Meyer, E. Mick, A. Miranda, F. Mulas, B.M. Neale, S.F. Nelson, M.C. O'Donovan, R.D. Oades, M.J. Owen, H. Palmason, Q. Qian, J.A. Ramos-Quiroga, A. Reif, T.J. Renner, M. Ribasés, S. Ripke, H. Roeyers, M. Romanos, J. Romanos, A. Rothenberger, C. Sánchez-Mora, R. Schachar, A. Scherag, S. Scherag, J. Sergeant, S.L. Smalley, J.S. Edmund, [No Value] Sonuga-Barke, H.-C. Steinhausen, A. Thapar, A. Todorov, I. Waldman, S. Walitza, Y. Wang, A. Warnke, N. Williams, L. Yang
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics  2015 vol.168 pp.492-507
Identification and functional characterisation of a novel dopamine beta hydroxylase gene variant associated with ADHD Janette Tong, Leigh-Anne McKinley, Tarrant Cummins, Beth Johnson, Natasha Matthews, Alasdair Vance, Helen Heussler, Michael Gill, Lindsey Kent, Mark Belgrove, Ziarih Hawi
World Journal of Biological Psychiatry 2015 
Identification and functional characterisation of a novel dopamine beta hydroxylase gene variant associated with attention deficit hyperactivity disorder Janette Tong, Leigh-Anne McKinley, Tarrant D. R. Cummins, Beth Johnson, Natasha Matthews, Alasdair Vance, Helen Heussler, Michael Gill, Lindsey Kent, Mark A. Bellgrove, Ziarih Hawi
World Journal of Biological Psychiatry 2015 vol.16 pp.610-618
Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder Robert Maier, Gerhard Moser, Guo-Bo Chen, Stephan Ripke, William Coryell, James B Potash, William A Scheftner, Jianxin Shi, Myrna M Weissman, Christina M Hultman, Mikael Landén, Douglas F Levinson, Kenneth S Kendler, Jordan W Smoller, Naomi R Wray, S Hong Lee, Lindsey Kent
American Journal of Human Genetics 2015 vol.96 pp.283-94
On the role of NOS1 ex1f-VNTR in ADHD – allelic, subgroup, and meta-analysis Heike Weber, S. Kittel-Schneider, J Heupel, L. Weißflog, Lindsey Kent, F. Freudenberg, A. Alttoa, A. Post, S. Herterich, Jan Haavik, Anne Halmøy, Ole Bernt Fasmer, Elisabeth Toverund Landaas, Stefan Johansson, Bru Cormand, Marta Ribasés, Cristina Sánchez-Mora, Josep Antoni Ramos-Quiroga, B. Franke, K-P. Lesch, Andreas Reif
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics  2015 vol.168 pp.445-458
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways Colm O'Dushlaine, Lizzy Rossin, Phil H. Lee, Laramie Duncan, Neelroop N. Parikshak, Stephen Newhouse, Stephan Ripke, Benjamin M. Neale, Shaun M. Purcell, Danielle Posthuma, John I. Nurnberger, S. Hong Lee, Stephen V. Faraone, Roy H. Perlis, Bryan J. Mowry, Anita Thapar, Michael E. Goddard, John S. Witte, Devin Absher, Ingrid Agartz, Huda Akil, Farooq Amin, Ole A. Andreassen, Adebayo Anjorin, Richard Anney, Verneri Anttila, Dan E. Arking, Philip Asherson, Maria H. Azevedo, Lena Backlund, Judith A. Badner, Anthony J. Bailey, Tobias Banaschewski, Jack D. Barchas, Michael R. Barnes, Thomas B. Barrett, Nicholas Bass, Agatino Battaglia, Michael Bauer, Monica Bayes, Frank Bellivier, Sarah E. Bergen, Wade Berrettini, Catalina Betancur, Thomas Bettecken, Joseph Biederman, Elisabeth B. Binder, Donald W. Black, Douglas H. R. Blackwood, Lindsey Kent,
Nature Neuroscience 2015 vol.18 pp.199-209
Biological overlap of attention-deficit/hyperactivity disorder and autism spectrum disorder Joanna Martin, Miriam Cooper, Marian L. Hamshere, Andrew Pocklington, Stephen W. Scherer, Lindsey Kent, Michael Gill, Michael J. Owen, Nigel Williams, Michael C. O'Donovan, Anita Thapar, Peter Holmans
Journal of the American Academy of Child and Adolescent Psychiatry 2014 vol.53 pp.761-770
Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder Amy B Hart, Eric R Gamazon, Barbara E Engelhardt, Pamela Sklar, Anna K Kähler, Christina M Hultman, Patrick F Sullivan, Benjamin M Neale, Stephen V Faraone, Harriet de Wit, Nancy J Cox, Abraham A Palmer, Lindsey Kent
Proceedings of the National Academy of Sciences of the United States of America 2014 vol.111 pp.5968-73
The genetic contribution of the NO system at the glutamatergic post-synapse to schizophrenia H. Weber, D. Klamer, F. Freudenberg, S. Kittel-Schneider, O. Rivero, C. -J. Scholz, J. Volkert, J. Kopf, J. Heupel, S. Herterich, R. Adolfsson, A. Alttoa, A. Post, H. Grussendorf, A. Kramer, A. Gessner, B. Schmidt, S. Hempel, C. P. Jacob, J. Sanjuan, M. D. Molto, K. -P. Lesch, C. M. Freitag, Lindsey Kent, A. Reif
European Neuropsychopharmacology 2014 vol.24 pp.65-85
DNA variation in the SNAP25 gene confers risk to ADHD and is associated with reduced expression in prefrontal cortex Ziarih Hawi, Natasha Matthews, Joseph Wagner, Robyn H. Wallace, Tim J. Butler, Alasdair Vance, Lindsey Kent, Michael Gill, Mark A. Bellgrove
PLoS One 2013 vol.8 
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs S. Hong Lee, Stephan Ripke, Benjamin M. Neale, Stephen V. Faraone, Shaun M. Purcell, Roy H. Perlis, Bryan J. Mowry, Anita Thapar, Michael E. Goddard, John S. Witte, Devin Absher, Ingrid Agartz, Huda Akil, Farooq Amin, Ole A. Andreassen, Adebayo Anjorin, Richard Anney, Verneri Anttila, Dan E. Arking, Philip Asherson, Maria H. Azevedo, Lena Backlund, Judith A. Badner, Anthony J. Bailey, Tobias Banaschewski, Jack D. Barchas, Michael R. Barnes, Thomas B. Barrett, Nicholas Bass, Agatino Battaglia, Michael Bauer, Monica Bayes, Frank Bellivier, Sarah E. Bergen, Wade Berrettini, Catalina Betancur, Thomas Bettecken, Joseph Biederman, Elisabeth B. Binder, Donald W. Black, Douglas H. R. Blackwood, Cinnamon S. Bloss, Michael Boehnke, Dorret I. Boomsma, Gerome Breen, Rene Breuer, Richard Bruggeman, Paul Cormican, Nancy G. Buccola, Lindsey Kent,
Nature Genetics 2013 vol.45 pp.984-+
High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression Marian L. Hamshere, Kate Langley, Joanna Martin, Sharifah Shameem Agha, Evangelia Stergiakouli, Richard J. L. Anney, Jan Buitelaar, Stephen V. Faraone, Klaus-Peter Lesch, Benjamin M. Neale, Barbara Franke, Edmund Sonuga-Barke, Philip Asherson, Andrew Merwood, Jonna Kuntsi, Sarah E. Medland, Stephan Ripke, Hans-Christoph Steinhausen, Christine Freitag, Andreas Reif, Tobias J. Renner, Marcel Romanos, Jasmin Romanos, Andreas Warnke, Jobst Meyer, Haukur Palmason, Alejandro Arias Vasquez, Nanda Lambregts-Rommelse, Herbert Roeyers, Joseph Biederman, Alysa E. Doyle, Hakon Hakonarson, Aribert Rothenberger, Tobias Banaschewski, Robert D. Oades, James J. McGough, Lindsey Kent, Nigel Williams, Michael J. Owen, Peter Holmans, Michael C. O'Donovan, Anita Thapar
American Journal of Psychiatry 2013 vol.170 pp.909-916
Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder Li Yang, Benjamin M Neale, Lu Liu, S Hong Lee, Naomi R Wray, Ning Ji, Haimei Li, Qiujin Qian, Dongliang Wang, Jun Li, Stephen V Faraone, Yufeng Wang, Alysa E. Doyle, Andreas Reif, Aribert Rothenberger, Barbara Franke, Edmund J S Sonuga-Barke, Hans-Christoph Steinhausen, Jan K Buitelaar, Jonna Kuntsi, Joseph Biederman, Klaus-Peter Lesch, Lindsey Kent, Philip Asherson, Robert D Oades, Sandra K Loo, Stan F Nelson, Stephen V Faraone, Susan L Smalley, Tobias Banaschewski, Alejandro Arias Vasquez, Alexandre Todorov, Alice Charach, Ana Miranda, Andreas Warnke, Anita Thapar, Benjamin M Neale, Bru Cormand, Christine Freitag, Eric Mick, Fernando Mulas, Frank Middleton, Hakon HakonarsonHakonarson, Haukur Palmason, Helmut Schäfer, Herbert Roeyers, James J McGough, Jasmin Romanos, Jennifer Crosbie, Jobst Meyer,
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics  2013 vol.162B pp.419-30
Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia Marian L. Hamshere, Evangelia Stergiakouli, Kate Langley, Joanna Martin, Peter Holmans, Lindsey Kent, Michael J. Owen, Michael Gill, Anita Thapar, Mick O'Donovan, Nick Craddock
British Journal of Psychiatry 2013 vol.203 pp.107-111
Don't give up on GWAS P Sullivan, Lindsey Kent
Molecular Psychiatry 2012 vol.17 pp.2-3
Genome-Wide Analysis of Copy Number Variants in Attention Deficit Hyperactivity Disorder Nigel M. Williams, Barbara Franke, Eric Mick, Richard J. L. Anney, Christine M. Freitag, Michael Gill, Anita Thapar, Michael C. O'Donovan, Michael J. Owen, Peter Holmans, Lindsey Kent, Frank Middleton, Yanli Zhang-James, Lu Liu, Jobst Meyer, Thuy Trang Nguyen, Jasmin Romanos, Marcel Romanos, Christiane Seitz, Tobias J. Renner, Susanne Walitza, Andreas Warnke, Haukur Palmason, Jan Buitelaar, Nanda Rommelse, Alejandro Arias Vasquez, Ziarih Hawi, Kate Langley, Joseph Sergeant, Hans-Christoph Steinhausen, Herbert Roeyers, Joseph Biederman, Irina Zaharieva, Hakon Hakonarson, Josephine Elia, Anath C. Lionel, Jennifer Crosbie, Christian R. Marshall, Russell Schachar, Stephen W. Scherer, Alexandre Todorov, Susan L. Smalley, Sandra Loo, Stanley Nelson, Corina Shtir, Philip Asherson, Andreas Reif, Klaus-Peter Lesch, Stephen V. Faraone
American Journal of Psychiatry 2012 vol.169 pp.195-204
Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder Josephine Elia, Joseph T. Glessner, Kai Wang, Nagahide Takahashi, Corina J. Shtir, Dexter Hadley, Patrick M. A. Sleiman, Haitao Zhang, Cecilia E. Kim, Reid Robison, Gholson J. Lyon, James H. Flory, Jonathan P. Bradfield, Marcin Imielinski, Cuiping Hou, Edward C. Frackelton, Rosetta M. Chiavacci, Takeshi Sakurai, Cara Rabin, Frank A. Middleton, Kelly A. Thomas, Maria Garris, Frank Mentch, Christine M. Freitag, Hans-Christoph Steinhausen, Alexandre A. Todorov, Andreas Reif, Aribert Rothenberger, Barbara Franke, Eric O. Mick, Herbert Roeyers, Jan Buitelaar, Klaus-Peter Lesch, Tobias Banaschewski, Richard P. Ebstein, Fernando Mulas, Robert D. Oades, Joseph Sergeant, Edmund Sonuga-Barke, Tobias J. Renner, Marcel Romanos, Jasmin Romanos, Andreas Warnke, Susanne Walitza, Jobst Meyer, Haukur Palmason, Christiane Seitz, Sandra K. Loo, Susan L. Smalley, Joseph Biederman, Lindsey Kent, Philip Asherson, Richard J. L. Anney, J. William Gaynor, Philip Shaw, Marcella Devoto, Peter S. White, Struan F. A. Grant, Joseph D. Buxbaum, Judith L. Rapoport, Nigel M. Williams, Stanley F. Nelson, Stephen V. Faraone, Hakon Hakonarson
Nature Genetics 2012 vol.44 pp.78-84
Investigating the Contribution of Common Genetic Variants to the Risk and Pathogenesis of ADHD Evangelia Stergiakouli, Marian Hamshere, Peter Holmans, Kate Langley, Irina Zaharieva, Ziarah Hawi, Lindsey Kent, Michael Gill, Nigel Williams, Michael J. Owen, Michael O'Donovan, Anita Thapar,
American Journal of Psychiatry 2012 vol.169 pp.186-194
Genome-wide association study in German patients with attention deficit/hyperactivity disorder Anke Hinney, André Scherag, Ivonne Jarick, Özgür Albayrak, Carolin Pütter, Sonali Pechlivanis, Maria R Dauvermann, Sebastian Beck, Heike Weber, Susann Scherag, Trang T Nguyen, Anna-Lena Volckmar, Nadja Knoll, Stephen V Faraone, Benjamin M Neale, Barbara Franke, Sven Cichon, Per Hoffmann, Markus M Nöthen, Stefan Schreiber, Karl-Heinz Jöckel, H-Erich Wichmann, Christine Freitag, Thomas Lempp, Jobst Meyer, Susanne Gilsbach, Beate Herpertz-Dahlmann, Judith Sinzig, Gerd Lehmkuhl, Tobias J Renner, Andreas Warnke, Marcel Romanos, Klaus-Peter Lesch, Andreas Reif, Benno G Schimmelmann, Johannes Hebebrand, Lindsey Kent
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics  2011 vol.156B pp.888-97