Prof David Harrison

Prof David Harrison
John Reid Chair of Pathology, Director of Research & Director of Laboratory Medicine, NHS Lothian



data source: symbiosis

Research Overview from research@st-andrews

Recent publications listed in research@st-andrews
Van Neste, C, Laird, A, O'Mahony, F, Van Criekinge, W, Deforce, D, Van Nieuwerbugh, F, Powles, T, Harrison, DJ, Stewart, GD & De Meyer, T 2017, 'Epigenetic sampling effects: nephrectomy modifies the clear cell renal cell cancer methylome' Cellular Oncology, vol First Online. DOI: 10.1007/s13402-016-0313-5
Gremel, G, Djureinovic, D, Niinivirta, M, Laird, A, Ljungqvist, O, Johannesson, H, Bergman, J, Edqvist, P-H, Navani, S, Khan, N, Patil, T, Sivertsson, Å, Uhlén, M, Harrison, DJ, Ullenhag, GJ, Stewart, GD & Pontén, F 2017, 'A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma' BMC Cancer, vol 17, 9. DOI: 10.1186/s12885-016-3030-6
Meehan, J, Ward, C, Turnbull, A, Bukowski-Wills, J, Finch, A, Jarman, EJ, Xintaropoulou, C, Martinez-Perez, C, Gray, M, Pearson, M, Mullen, P, Supuran, CT, Carta, F, Harrison, DJ, Kunkler, IH & Langdon, S 2017, 'Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells' Oncotarget, vol 8, no. 26, pp. 42857-42875. DOI: 10.18632/oncotarget.17143
Jamieson, LE, Camus, VL, Bagnaninchi, PO, Fisher, KM, Stewart, GD, Nailon, WH, McLaren, DB, Harrison, DJ & Campbell, CJ 2016, 'Targeted SERS nanosensors measure physicochemical gradients and free energy changes in live 3D tumor spheroids' Nanoscale, vol 8, no. 37, pp. 16710-16718. DOI: 10.1039/C6NR06031E
Wilkie, RP, Neal, A, Johnston, CA, Voûte, N, Lancefield, CS, Stell, M, Medda, F, Makiyi, EF, Turner, E, Ojo, OS, Slawin, AMZ, Lebl, T, Mullen, P, Harrison, DJ, Ireland, CM & Westwood, NJ 2016, 'Total synthesis of dehaloperophoramidine using a highly diastereoselective Hosomi-Sakurai reaction' Chemical Communications, vol 52, no. 71, pp. 10747-10750. DOI: 10.1039/c6cc05747k
Van Neste, L, Partin, AW, Stewart, GD, Epstein, JI, Harrison, DJ & Van Criekinge, W 2016, 'Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies' The Prostate, vol 76, no. 12, pp. 1078-1087. DOI: 10.1002/pros.23191
Martínez-Pérez, C, Ward, C, Turnbull, AK, Mullen, P, Cook, G, Meehan, J, Jarman, EJ, Thomson, PIT, Campbell, CJ, McPhail, D, Harrison, DJ & Langdon, SP 2016, 'Antitumour activity of the novel flavonoid oncamex in preclinical breast cancer models' British Journal of Cancer, vol 114, no. 8, pp. 905-916. DOI: 10.1038/bjc.2016.6
Gravis, G, Chanez, B, Derosa, L, Beuselinck, B, Barthelemy, P, Laguerre, B, Brachet, P-E, Joly, F, Escudier, B, Harrison, DJ, Laird, A, Vasudev, N, Ralph, C, Larkin, J, Lote, H, Salem, N, Walz, J, Thomassin, J, Sfumato, P, Stewart, GD, Boher, JM & Renal Cross Channel Group 2016, 'Effect of glandular metastases on overall survival of patients with metastatic clear cell renal cell carcinoma in the antiangiogenic therapy era' Urologic Oncology: Seminars and Original Investigations, vol 34, no. 4, pp. 167.e17-167.e23. DOI: 10.1016/j.urolonc.2015.10.015
Stewart, GD, Powles, T, Van Neste, C, Meynert, A, O'Mahony, F, Laird, A, Deforce, D, Van Nieuwerburgh, F, Trooskens, G, Van Criekinge, W, De Meyer, T & Harrison, DJ 2016, 'Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer' Oncotarget, vol 7, no. 18. DOI: 10.18632/oncotarget.8308
Caie, PD & Harrison, DJ 2016, Next-generation pathology. in U Schmitz & O Wolkenhauer (eds), Systems Medicine. Methods in Molecular Biology, vol. 1386, Humana Press, pp. 61-72. DOI: 10.1007/978-1-4939-3283-2_4
Khalil, HS, Langdon, SP, Goltsov, A, Soininen, T, Harrison, DJ, Brown, J & Deeni, YY 2016, 'A novel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2 function in ovarian cancer cells' Oncotarget, vol 7, no. 46, pp. 75874-75901. DOI: 10.18632/oncotarget.12425
Jamieson, LE, Harrison, DJ & Campbell, CJ 2015, 'Chemical analysis of multicellular tumour spheroids' Analyst, vol 140, no. 12, pp. 3910-3920. DOI: 10.1039/c5an00524h
Jamieson, LE, Bell, AP, Harrison, DJ & Campbell, CJ 2015, Monolayer to MTS: using SEM, HIM, TEM and SERS to compare morphology, nanosensor uptake and redox potential in MCF7 cells. in C Kurachi, K Svanberg, BJ Tromberg & VS Bagnato (eds), Biophotonics South America. Proceedings of SPIE, vol. 9531, SPIE, Biophotonics South America, Rio de Janeiro, Brazil, 23 May. DOI: 10.1117/12.2180944